Peliosis Hepatis: Spectrum of Imaging Findings

Iannaccone, Riccardo; Federle, Michael P.; Brancatelli, Giuseppe; Matsui, Osamu; Fishman, Elliot K.; Narra, Vamsidar R.; Grazioli, Luigi; McCarthy, Shirley; Piacentini, Francesca; Maruzzelli, Luigi; Passariello, Roberto; Vilgrain, Valérie

doi:10.2214/ajr.05.0167

Cited by 152 publications

(171 citation statements)

References 8 publications

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“…In the case of hemorrhage, PH lesions appear as hyperattenuating structures on unenhanced CT. Hepatic angiography discloses a typical appearance of PH lesions that accumulate contrast in the late arterial or parenchymal phase and retain it through the early venous phase. [7,8] In our patient, an abdomen CT scan showed hepatomegaly with heterogeneous enhancement of liver parenchyma. A Liver biopsy is the most rewarding tool in diagnosing PH.…”

Section: Case Reportmentioning

confidence: 50%

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Peliosis hepatis complicating pregnancy: A rare entity

Butt

Luck

Hassan

et al. 2017

Journal of Translational Internal Medicine

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Peliosis hepatis (PH) is a rare, benign condition of the liver characterized by the presence of blood-filled lacunar spaces in the parenchyma. It usually has a chronic presentation and is a rare cause of portal hypertension reported in adult patients. Its etiology is diverse and ranges from infectious agents to tumors to toxic substances and anabolic steroids; however, the cause remains unclear in 25-50% of patients. Similarly, the symptomatology and imaging findings are diverse. Biopsy is the definitive test to diagnose the condition. Herein, we present a case of a young female presenting in her seventh month of gestational amenorrhea with signs of portal hypertension and subsequently diagnosed to have PH. She was managed conservatively and delivered her baby normally. Later, she presented with spontaneous bacterial peritonitis and hepatic encephalopathy and developed hepatorenal syndrome. She later succumbed to her illness. The condition should be kept in the differential diagnosis of the atypical liver masses and liver diseases causing portal hypertension.

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Section: Case Reportmentioning

confidence: 50%

“…Prognosis is largely determined by the underlying cause and is generally guarded. [6][7][8][9][10] Herein, we present a case of a young female presenting in her seventh month of gestational amenorrhea with signs of portal hypertension and subsequently diagnosed to have PH.…”

Section: Introductionmentioning

confidence: 99%

Peliosis hepatis complicating pregnancy: A rare entity

Butt

Luck

Hassan

et al. 2017

Journal of Translational Internal Medicine

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“…Previous reports have also described PH patients with no predisposing condition [13,18]. In fact, no associated condition can be identified in 20-50 % of patients with PH [18,19].…”

Section: F-fdgmentioning

confidence: 97%

“…However, cholestasis, hepatic failure, or hemorrhagic necrosis might also be present [17][18][19]. Bacillary peliosis can contain clumps of microorganisms (Bartonella henselae or B. quintana) that may present with lymphadenopathy [20].…”

Section: F-fdgmentioning

confidence: 99%

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Peliosis Hepatis Shows Isometabolism on 18F-FDG PET/CT: Two Case Reports

Seo

Lee

Han

et al. 2014

Nucl Med Mol Imaging

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Peliosis hepatis (PH) is a rare benign disease that is characterized by multiple blood-filled cystic spaces in the hepatic parenchyma. It is also characterized by a range of radiologic findings that might mimic various diseases, including metastatic liver disease and hepatocellular carcinoma. The findings of PH on 18 F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) are not well reported. We here report two cases of biopsy-proven PH. Both patients had been treated for cancer (advanced gastric carcinoma and rectal adenocarcinoma), and followup CT of both cases revealed hepatic lesions with the possibility of metastasis. Examination of 18 F-FDG PET/CT images suggested that the lesions were isometabolic, having metabolism similar to that of adjacent hepatic parenchyma. The outcomes of hepatic core-needle biopsies were consistent with peliosis hepatis.

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