Pediatric liver tumors

Pattern and Outcome of Primary Liver Tumors in Children: Eight–year experience at South Egypt Cancer Institute

“…In contrast, the SIOPEL group advocates neoadjuvant therapy in all patients (13). Also, HBs are chemosensitive tumors, and most of the initially unresectable tumors become amenable to complete surgical resection following the current preoperative chemotherapy regimens, mostly with cisplatin and doxorubicin (28). Chemotherapy causes the tumor not only to shrink in size but also to become more clearly defined and less friable which is reflected in safer surgery with reduced blood loss (29).…”

Pattern and Outcome of primary Liver Tumors in Children: A 10 years report from single oncology center in Upper Egypt

“…Although complete surgical resection is considered the most important factor predicting patients who would achieve cure, yet response to chemotherapy is another paramount factor affecting survival in those patients [25] [26]. HBs are chemosensitive tumors, and most of the initially unresectable tumors become amenable to complete surgical resection following the current preoperative chemotherapy regimens, mostly with cisplatin and doxorubicin [24][25] [26].…”

Similar response rates and superior early progression‐free survival with gemcitabine, dexamethasone, and cisplatin salvage therapy compared with carmustine, etoposide, cytarabine, and melphalan salvage therapy prior to autologous stem cell transplantation for recurrent or refractory Hodgkin lymphoma

“…Liver lesions in children and adolescents present an unusual and interesting diagnostic spectrum, presenting most commonly as palpable abdominal mass, upper abdominal pain, fever, or symptoms of biliary obstruction. Abdominal ultrasound is considered as the best screening technique for children who present with an abdominal mass, identifying whether the mass is solid or cystic as well as the extent of tumor within the liver 17. Correlation of cytopathological features of pediatric liver lesions with clinical and radiological findings makes FNA a valuable diagnostic tool 18…”