PeakAL: Protons I Have Known and Loved - Fifty Shades of Grey-Market Spectra

Identification of seven psychedelic 2,5‐dimethoxy‐phenylethyl‐amine‐based designer drugs via benchtop 1H nuclear magnetic resonance spectroscopy

“…While the NMR data for some 2C‐X representatives listed in Table 1 has been communicated in the literature (see Section 4), to the best of our knowledge, those of 2C‐D·HCl [ 19,20 ] ( 3 ) and 2C‐P·HCl [ 20 ] ( 5 ) has not been discussed in a scientific publication and the low‐field NMR data has not been observed.…”

“…However, by applying a negative exponential apodization the apparent singlets of the aromatic signal at 6.81 ppm and the methyl group in position 4, para to the ethylamine, at 2.13 ppm appear as doublets with a coupling constant of 4 J HH = 0.7 Hz (see supporting information, SI), which is similar to the observations of Chapman and Avanes. [ 20 ] For a reported 100 MHz NMR spectrum of amphetamine derived 2,5‐dimethoxy‐4‐methylamphetamine (DOM) the aromatic hydrogen atoms with similar electronic environment were observed as one single‐peak signal by the authors. [ 21 ] Accordingly, the near identical chemical shift of the aromatic signals of 2C‐D·HCl ( 3 ) can be explained by the symmetry of the molecular structure.…”