Peak Bone Mineral Density and Its Determinants in an Asian Indian Population

The Association Between Body Composition, 25(OH)D, and PTH and Bone Mineral Density in Black African and Asian Indian Population Groups

“…Several investigators have shown that black men and women have greater bone mass, whereas AIs have lower bone mass than white subjects (7,35,36). The greater bone density in Africans may be protective of fractures, given that fracture rates are similar in AI and Caucasian women (37), whereas BA have lower fracture rates compared with other ethnic groups (3).…”

Association of Polymorphisms in the Vitamin D Receptor Promoter with Idiopathic Short Stature

“…The role of promoter region, one part of the VDR gene, is a regulation of VDR gene transcriptional activity in the intestinal mucosa as well (5, 24-27). The well-known two SNPs located in the VDR promoter region are rs11568820 located at Cdx-2 binding site locus and rs4516035 located at -1012 locus.…”

“…The well-known two SNPs located in the VDR promoter region are rs11568820 located at Cdx-2 binding site locus and rs4516035 located at -1012 locus. These SNPs are also related to bone mineral density (BMD) and modulation of calcium homeostasis (24-27). In this study, we hypothesized that promoter region of the VDR gene is also associated with height like other region of the VDR gene.…”

Mechanisms and implications of bone adipose tissue-mineral relationships

“…Second, since DXA scanning is a two-dimensional process the amount of bone mineral is expressed in relation to a projected bone area (areal density (areal BMD); g/cm 2 ), from which the total mineral content (BMC) of the bone or region of interest can be calculated (BMC ¼ areal BMD Â bone projected area). Some studies have chosen to use only areal BMD 8,11,13 to report their results, as in the study of Shen et al,…”

“…It also varies according to the type of bone [8][9][10] and even region within the same bone. [8][9][10] Peak bone mass of the lumbar spine has generally been reported to occur at 20-40 years [8][9][10][11][12][13][14] but at the femoral neck, it has often been reported to occur earlier at around 20 years or even earlier. [8][9][10] There appears to be little information about age of the peak bone mass of the pelvis.…”