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Cited by 29 publications
(19 citation statements)
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“…Previous studies have suggested that the precuneus, which is a core hub in DMN, plays an important role in a diverse array of highly integrated functions (Leech and Sharp, 2014) and is relevant for episodic memory retrieval (Greicius et al, 2004). Longitudinal studies have indicated that memory declines are related to decreased functional connectivity within DMN, particularly the precuneus/PCC (Persson et al, 2014;Bernard et al, 2015). The positive relationships indicated that more the FCS decreased in precuneus, greater the decline in global function with aging.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Previous studies have suggested that the precuneus, which is a core hub in DMN, plays an important role in a diverse array of highly integrated functions (Leech and Sharp, 2014) and is relevant for episodic memory retrieval (Greicius et al, 2004). Longitudinal studies have indicated that memory declines are related to decreased functional connectivity within DMN, particularly the precuneus/PCC (Persson et al, 2014;Bernard et al, 2015). The positive relationships indicated that more the FCS decreased in precuneus, greater the decline in global function with aging.…”
Section: Discussionmentioning
confidence: 99%
“…Longitudinal studies have indicated that decreased functional connectivity within DMN, particularly the precuneus/posterior cingulate cortex (PCC), was correlated with memory declines (Persson et al, 2014;Bernard et al, 2015), episodic memory, and processing speed changes (Staffaroni et al, 2018). However, the relationship between longitudinal changes of whole brain FCS and longitudinal changes of cognitive performance scores, especially global cognition, in very old cognitively unimpaired people are poorly understood.…”
Section: Introductionmentioning
confidence: 99%
“…The PCC plays a crucial role in memory function and has strong interconnections with other memory-related structures, such as the parahippocampal formation in subserving episodic memory retrieval (Torta and Cauda, 2011; Shapira-Lichter et al ., 2013). A previous study suggests that age-related memory decline in older adults is associated with decreased connectivity between the PCC and parietal regions (Bernard et al ., 2015). In addition, the mPFC also plays an important role in the retrieval of long-term memories and the consolidation of a wide range of memories (Euston et al ., 2012).…”
Section: Discussionmentioning
confidence: 99%
“…This approach allows for contrasting functional connectivity between subjects with declining and stable memory. Functional connectivity in regions of the DMN has been found to be lower in participants with declining memory than in participants with stable memory (Bernard et al, 2015) . Furthermore, the reverse pattern can be seen for connectivity within the hippocampus: older adults with stable memory showed lower connectivity within the hippocampus, a pattern that makes them more similar to young adults (Salami et al, 2014) .…”
Section: Cognition and Functional Connectivitymentioning
confidence: 94%