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Cited by 391 publications
(242 citation statements)
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References 17 publications
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“…However, some patients still die of their disease, particularly those with larger tumors. The preliminary tumor control in patients treated with IMRT has been promising; however, when analyzing the patterns of failure, studies have shown that tumors tend to recur within the GTV, which can lead to greater distant metastasis rates (35,36,(55)(56)(57)(58)(59).…”
Section: Discussionmentioning
confidence: 99%
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“…However, some patients still die of their disease, particularly those with larger tumors. The preliminary tumor control in patients treated with IMRT has been promising; however, when analyzing the patterns of failure, studies have shown that tumors tend to recur within the GTV, which can lead to greater distant metastasis rates (35,36,(55)(56)(57)(58)(59).…”
Section: Discussionmentioning
confidence: 99%
“…Investigators have suggested increasing the dose delivered to the GTV to further improve LRC (35,36,60). However, owing to fear of unwarranted complications that could result from an increased radiation dose to the GTV, such a strategy has not been implemented in clinical trials.…”
Section: Discussionmentioning
confidence: 99%
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“…Following definitive RT the majority of HNC failures are infield and occur within the 95% dose coverage region [1][2][3][4][5]. In order to improve treatment outcomes a better understanding of why these infield failures occur is needed.…”
Section: Introductionmentioning
confidence: 99%
“…Recent studies have demonstrated that the treatment of OPC with IMRT can achieve very high rates of locoregional tumor control, representing an obvious improvement compared with the rates reported in the past in series using 'standard' radiotherapy [8][9][10]. These improvements may be related to better dosimetric coverage of the target compared with conventional radiotherapy [2,11].…”
Section: Imrt In Oropharyngeal Carcinomamentioning
confidence: 98%