2018
DOI: 10.3389/fonc.2018.00302
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: Introduction: Distant metastasis remains the major cause of treatment failure in esophageal cancer, though there have been few large-scale studies of the patterns of distant metastasis in different histological types. We investigated the patterns of distant metastasis in esophageal adenocarcinoma (AC) and squamous cell carcinoma (SCC) using a population-based approach.Methods: Patients with de novo stage IV esophageal cancer at diagnosis were identified using the Surveillance, Epidemiology, and End Results dat… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

9
45
1

Year Published

2018
2018
2022
2022

Publication Types

Select...
7
2
1

Relationship

0
10

Authors

Journals

citations
Cited by 58 publications
(55 citation statements)
references
References 32 publications
9
45
1
Order By: Relevance
“…Moreover, LN metastasis was shown to weigh more than other pathological factors in predicting liver metastasis. LN metastasis was proved as a common sign before distant metastases,31,32 suggesting that greater attention concerning distant metastases should be paid in PDAC patients with LN metastasis. Regarding the common prognostic biomarkers, such as carbohydrate antigen 19-9 (CA19-9) and CA125, they were shown to be associated with tumor burden and advanced stages in patients with PDAC 27,33,34.…”
Section: Discussionmentioning
confidence: 99%
“…Moreover, LN metastasis was shown to weigh more than other pathological factors in predicting liver metastasis. LN metastasis was proved as a common sign before distant metastases,31,32 suggesting that greater attention concerning distant metastases should be paid in PDAC patients with LN metastasis. Regarding the common prognostic biomarkers, such as carbohydrate antigen 19-9 (CA19-9) and CA125, they were shown to be associated with tumor burden and advanced stages in patients with PDAC 27,33,34.…”
Section: Discussionmentioning
confidence: 99%
“…[2] A recent large cohort study reported a prevalence of 3.4% of brain metastases (BM) among patients with EC, and the histological subtype (adeno vs squamous cell carcinoma) influenced the probability of brain metastases. [3] Only scarce data are available regarding the manifestation pattern of BM from EC, with most studies describing solitary metastases in the majority of the cases; however these caused neurological symptoms in all patients described. Until now, patients with gastrointestinal tumors do not undergo regular screening for BM according to current guidelines.…”
Section: Introductionmentioning
confidence: 99%
“…Moreover, LN metastasis was shown to weigh more than other pathological factors in predicting liver metastasis. LN metastasis was proved as a common sign before distant metastases, 31,32 suggesting that greater attention concerning distant metastases should be paid in PDAC patients with LN metastasis. Regarding the common prognostic biomarkers, such as carbohydrate antigen 19-9 (CA19-9) and CA125, they were shown to be associated with tumor burden and advanced stages in patients with PDAC.…”
Section: Discussionmentioning
confidence: 99%