Patterns of breast, prostate and cervical cancer incidence and mortality in Colombia: An administrative registry data analysis

Abstract

Background Cancer is widely recognized as a global public health problem. Breast, prostate and cervical cancer are among the most frequent types in developing countries. Assessing their incidence and mortality by regions and municipalities is important to guide evidence-based health policy. Our aim was to describe the incidence and mortality trends for breast, cervical and prostate cancer across regions and municipalities in Colombia during 2018. Methods We performed a cross-sectional analysis with data from people with breast, prostate or cervical cancer, reported to the National Administrative Cancer Registry during 2018. A descriptive analysis was performed. Age-standardized incidence and mortality rates were estimated at national, regional and municipal levels. Finally, we identify the regions and municipalities with significantly higher or lower incidence and mortality rates compared to national estimations. Results Breast cancer was the most frequent type among all new cases and deaths in Colombia. Breast, prostate and cervical cancer incidence and mortality rates were: 18,69 (CI 95%: 18,15–19,25) and 10,48 (CI 95%: 10,07–10,91); 11,34 (CI 95%: 10,90 − 11,78) and 7,58 (CI 95%: 7,22 − 7,96); 5,93 (CI 95%: 5,62 − 6,25) and 4,31 (CI 95%: 4,05 − 4,58), respectively. Eastern region had both, incidence and mortality rates, significantly lower than national for all types of cancer. By municipalities, there were a heterogeneous pattern. Nonetheless, Agua de Dios (Cundinamarca), had one of the highest incidence rates for all types. Conclusions We observed clear differences in cancer incidence and mortality across regions and municipalities, depending on each type of cancer. Our findings are important to improve screening coverage, early detection and treatment in the country.

Application of Box-Behnken design for optimization of phenolics extraction from Leontodon hispidulus in relation to its antioxidant, anti-inflammatory and cytotoxic activities

“…The formation of reactive oxygen species is an essential mechanism through which inflammation induces carcinogenesis 18 . According to "Global Cancer Observatory" (GLOBOCAN), 18.1 million new cases and 9.6 million deaths were reported in 2018 worldwide 19 . In our study, we evaluated the potential activity of the plant against two types of human cancer, prostate and cervical carcinoma.…”

Prevalence of Lung Cancer in Colombia and a New Diagnostic Algorithm Using Health Administrative Databases: A Real-World Evidence Study

“…However, the estimation methods used by the first two institutions were based on data obtained from samples of a limited number of patients with lung cancer attended at various IPSs around the country, thus introducing possible bias to the calculated rates [23,24]. Furthermore, prevalence rates reported by CAC were based on data provided by EPS; although it included information from 98% of the total population affiliated with the health system, these reported data could have underestimated the real prevalence, as it depended on passive reporting [25,26]. In the case of our research, the identification process involved the use of algorithms that take information from the usage of the reported services.…”