Pattern of Vascular Insufficiency on Ultrasound Colour Doppler and Computed Tomographic Angiography in Patients with Diabetic Foot and Its Clinical Outcome

Seth, Abhinav; Attri, Ashok Kumar; Kataria, Hanish; Kochhar, Suman; Kaur, Navdeep

doi:10.4172/2167-7964.1000269

Cited by 2 publications

(8 citation statements)

References 16 publications

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“…These values were not significantly different from those of controls. The arterial diameter values are broadly similar to those reported by Seth et al (PTA = 2.2 ± 0.9 mm, DPA = 1.8 ± 0.8 mm),[ 20 ] and Leoniuk et al (PTA = 2.2 ± 0.42 mm, DPA = 1.98 ± 0.39 mm). [ 14 ]…”

Section: Discussionsupporting

confidence: 87%

“…Plaques were present in the DPA of 52 (55.3%) diabetic limbs. Arterial intimal thickening, plaques, and calcifications were also reported by some of the previous researchers including Seth et al (47.7% in DPA, 50.8% in PTA),[ 20 ] Janssen (54%),[ 25 ] and Das et al (73.3%). [ 28 ] The disparity in the plaque rates may be due to the differences in patient age, diabetes duration, and co-existing systemic hypertension and hyperlipidaemia in some of the other studies.…”

Section: Discussionsupporting

confidence: 61%

“…These two arteries were also the only vessels assessed in some of the previous studies. [ 14 20 27 ] Janssen[ 25 ] examined the anterior tibial artery (ATA) and the PTA only, while Das et al [ 28 ] analysed the ATA, PTA, and the DPA. Some previous studies evaluated all the lower limb arteries from the common femoral artery (CFA) to the DPA.…”

Section: Discussionmentioning

confidence: 99%

“…Although LEPAD is said to be more prevalent in the femoropopliteal arteries, angiopathic changes in the infrapopliteal arteries (especially the DPA) are often more severe in diabetic limbs and are more predictive of the risk of amputation. [ 7 20 28 ] Even among the studies that examined all the lower limb arteries, two[ 7 31 ] noted that changes in the DPA were the most significant. In a third study,[ 32 ] DPA changes were second to the femoropopliteal arterial abnormalities in hemodynamic significance.…”

Section: Discussionmentioning

confidence: 99%

“…Patients with type 2 diabetes mellitus were excluded if they had the following: previous revascularization surgery, history of foot trauma, co-existing Buergers disease (based on clinical history of on-and-off pain in the feet and hands in a patient who consumes tobacco), co-existing with systemic hypertension, and co-existing with sickle cell disease. [ 7 20 ]…”

Section: Methodsmentioning

confidence: 99%

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Comparative Doppler ultrasound findings of foot arteries in patients with type 2 diabetes mellitus and normoglycaemic patients

Idowu¹,

Oduola-Owoo

Adeyomoye

et al. 2022

J West Afr Coll Surg

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Aim of the Study: The aim of this study was to investigate lower extremity peripheral artery disease (LEPAD) in the foot arteries of patients with type 2 diabetes mellitus, with and without clinical symptoms of arterial insufficiency, using triplex Doppler ultrasound. Materials and Methods: Forty-seven consecutive adult subjects with type 2 diabetes mellitus (T2DM) and 47 age-matched and sex-matched non-diabetic controls were recruited (94 limbs each). Ankle-brachial index (ABI), fasting blood glucose assay, glycated haemoglobin assay and triplex sonography of the dorsalis pedis artery (DPA) and the distal posterior tibial artery (PTA) in both feet were performed. Results: The mean age of the subjects and controls were 60.21 ± 7.68 years and 56.81 ± 9.05 years ( P > 0.05). The mean duration of diabetes mellitus was 10.4 ± 5.8 years. Crampy calf pain was the most common presenting symptom. Twenty-one (22.3%) of the 94 limbs of T2DM subjects had an abnormal ABI. Abnormal triplex Doppler waveform was seen in more than half of the PTA (57/94; 60.6%) and DPA (55/94; 58.5%). Forty-one (43.6%) of the 94 diabetic limbs had plaques in the PTA, while plaques were present in the DPA of 52 (55.3%) diabetic limbs. Conclusion: LEPAD is common in T2DM with a higher prevalence on triplex Doppler sonography compared to ABI values.

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Section: Discussionsupporting

confidence: 87%

Section: Discussionsupporting

confidence: 61%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 3 more Smart Citations

Comparative Doppler ultrasound findings of foot arteries in patients with type 2 diabetes mellitus and normoglycaemic patients

Idowu¹,

Oduola-Owoo

Adeyomoye

et al. 2022

J West Afr Coll Surg

View full text Add to dashboard Cite

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The Correlation of Short-Chain Fatty Acids with Peripheral Arterial Disease in Diabetes Mellitus Patients

Muradi

Jasirwan

Simanjuntak

et al. 2022

Life

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Diabetes mellitus (DM) is a significant risk factor for peripheral arterial disease (PAD). PAD affects 20% of DM patients over 40 and has increased by 29% in the last 50 years. The gut microbiota produces short-chain fatty acids (SCFAs) that affect atherosclerosis. SCFA inhibits inflammation, which contributes to atherosclerosis. This study tried to link feces SCFA levels to atherosclerosis in people with diabetes with peripheral arterial disease (PAD). The study included 53 people with diabetes and PAD: gas chromatography-mass spectrometry measured acetate, butyrate, and propionate levels in feces samples (GC-MS). There was a positive correlation between random blood glucose (RBG) levels, peak systolic velocity (PSV), volume flow (VF), plaque, relative and absolute acetate, relative valerate, butyrate, and propionate. This supports the idea that elevated SCFA levels in type 2 diabetic (T2D) patients reduce adipose tissue inflammation and cholesterol metabolism, contributing to atherosclerosis pathogenesis. We conclude that increased fecal SCFA excretion is linked to cardiovascular disease. To determine the causal effect correlation of the SCFA with clinical and laboratory parameters for PAD in DM patients, compare the SCFA in plasma and feces, and account for confounding variables, a specific method with larger sample sizes and more extended follow-up periods is required.

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Pattern of Vascular Insufficiency on Ultrasound Colour Doppler and Computed Tomographic Angiography in Patients with Diabetic Foot and Its Clinical Outcome

Cited by 2 publications

References 16 publications

Comparative Doppler ultrasound findings of foot arteries in patients with type 2 diabetes mellitus and normoglycaemic patients

Comparative Doppler ultrasound findings of foot arteries in patients with type 2 diabetes mellitus and normoglycaemic patients

The Correlation of Short-Chain Fatty Acids with Peripheral Arterial Disease in Diabetes Mellitus Patients

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