Pattern of regional metastases from cutaneous squamous cell carcinoma of the head and neck

Abstract

SCC of the skin of the head and neck with regional metastases has a high incidence of occult metastases in the parotid gland and the neck. Patients with metastases in both sites have a poor prognosis.

Predicting the pattern of regional metastases from cutaneous squamous cell carcinoma of the head and neck based on location of the primary

“…Furthermore, opinions differ as to the appropriate extent of neck dissection. [9][10][11][12] The current study represents a single institution analysis of prospectively collected data on the results of 295 neck dissections for cutaneous SCCHN. It was undertaken to determine the patterns of spread in the cervical lymph nodes, the relationship to the location of the primary tumor, and the morbidity associated with the procedure.…”

“…A multicenter study involving our institution previously recommended a supraomohyoid neck dissection in patients with anterolateral primaries and a comprehensive neck dissection for posterior primaries 9 while several other authors have recommended selective dissection of level I-II or I-III nodes in this setting regardless of the site of the primary tumor. [10][11][12] The most important outcome in this study revolves around the absence of level IV or V metastases in cPþN0 patients with pathologically negative nodes in levels II and III. Based on these findings, we support the use of elective level II/III dissection to stage the neck and determine the extent of adjuvant radiotherapy.…”

“…A multicenter study involving our institution previously recommended a supraomohyoid neck dissection in patients with anterolateral primaries and a comprehensive neck dissection for posterior primaries 9 while several other authors have recommended selective neck dissection in this setting without taking into account the location of the primary tumor. [10][11][12] The primary aim of this study was to determine if a more selective approach to the neck, dissecting only levels II and III in cPþN0 patients is feasible. To test this hypothesis, we analyzed the pattern and frequency of regional lymph node metastases from cutaneous SCCHN according to the location of the primary site.…”

Maxillofacial Metastases: A Retrospective Review of One Institution's 15-Year Experience

“…45 Serving as the first echelon of metastases from the upper third of the face, including the scalp, cheek, and eyelid, it has been found that in general, skin cancer accounts for 50% of metastasis to the parotid gland. 46 These metastatic cells continue their descent and eventually seed to the ipsilateral cervical nodes. An obvious carcinoma seen on the face can make the diagnosis easier.…”

Advanced Squamous Cell Carcinoma of the Skin

“…(O'Hara, Ferlito et al 2010) Cervical neck node disease without parotid involvement can be seen in 18 to 41% of patients. (Andruchow, Veness et al 2006;Vauterin, Veness et al 2006) In this situation, the recommendation is the treatment of the neck with classic or modified radical dissection associated with elective parotidectomy in primaries of anterior regions of scalp and lateral face (Barzilai, Greenberg et al 2005;Jennings and Schmults 2010). Fig.…”