Pattern of allergic rhinitis among children in Ekiti, Nigeria

Adegbiji, Waheed Atilade; Olajide, Gabriel Toye; Olajuyin, Anthony Oyebanji; Aremu, Shuaib Kayode; Olusola, Akanbi Ganiyu

doi:10.1016/j.ijporl.2018.01.014

Cited by 18 publications

(11 citation statements)

References 36 publications

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“…Some scholars believe that allergic inflammation is not limited to the site where it initially occurs, and can be secondary to non-allergic reactions throughout the body (11). A number of reports have indicated that if not treated in time, allergic rhinitis can be complicated with asthma, sinusitis, otitis media, pharyngitis, conjunctivitis, and other diseases (12)(13)(14).…”

Section: Discussionmentioning

confidence: 99%

Expression and clinical significance of VCAM-1, IL-6, and IL-17A in patients with allergic rhinitis

Gao

Zhang³

et al. 2021

Ann Palliat Med

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Background: Allergic rhinitis is a chronic inflammatory disease with a high incidence, affecting the quality of life of patients. The aim of the present study was to explore the expression and clinical significance of vascular endothelial cell adhesion molecule-1 (VCAM-1), interleukin (IL)-6, and IL-17A in patients with allergic rhinitis.Methods: A total of 180 patients with allergic rhinitis, who were admitted to our hospital from March 2017 to March 2020, were enrolled as the observation group. Patients were further divided into 3 subgroups according to the degree of severity of allergic rhinitis as follows: the mild group (n=66), the moderate group (n=60), and the severe group (n=54). During the same period, 188 people without allergic rhinitis, who underwent physical examination in our hospital, were enrolled as the control group. VCAM-1, IL-6, and IL-17A levels were compared between these groups, and the correlation between the 3 levels and allergic rhinitis was analyzed.Results: VCAM-1, IL-6, and IL-17A levels in the observation group were significantly higher than those in the control group, and the difference was statistically significant (P<0.05). Comparison results of VCAM-1, IL-6 and IL-17A levels among the 3 groups were as follows: mild group < moderate group < severe group, and the differences between the three groups were significant (P<0.05). Pearson linear correlation showed that serum levels of VCAM-1, IL-6 and IL-17A were positively correlated with ARIA (P<0.05). Parent history of allergic rhinitis, living environment pollution, abnormally elevated VCAM-1, abnormally elevated IL-6 and abnormally elevated IL-6 were the related risk factors for inducing allergic rhinitis (P<0.05).Conclusions: VCAM-1, IL-6, and IL-17A play important roles in allergic rhinitis, and the concentration will increase with disease progression. Clinical testing of VCAM-1, IL-6, IL-17A should be increased to improve the diagnostic rate for early allergic rhinitis and to prevent disease progression.

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Section: Discussionmentioning

confidence: 99%

Expression and clinical significance of VCAM-1, IL-6, and IL-17A in patients with allergic rhinitis

Gao

Zhang³

et al. 2021

Ann Palliat Med

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“…cia; la etiología es variada. Un adecuado interrogatorio y un minucioso examen físico son suficientes para hacer el diagnóstico en la mayoría de los casos 11 . El dolor en la garganta también es señalado, por algunos autores, como un síntoma habitual en estas consultas, sobre todo en población infantil 17 .…”

Section: Resultsunclassified

“…El dolor crónico está asociado con ansiedad y depresión, en tanto el dolor agudo es más frecuentemente asociado con ansiedad. Existe evidencia de la relación del dolor de oídos y el de garganta con síntomas psicológicos, como causa o consecuencia del padecimiento [9][10][11] .…”

Section: Introductionunclassified

Factores psicosociales en pacientes de un servicio de otorrinolaringología

Vázquez-Machado

Cossa

Pichs-Llópiz³

2019

Rev. chil. neuro-psiquiatr.

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Background:The psychological symptoms are present at patients with otorhinolaryngologic manifestations according to reports of some investigations. Objective: To describe the psychosocial factors in otorhinolaringology outpatients. Methods: It is a cross-sectional study with 138 outpatients who visited the department of otorhinolaryngology in Nampula Central Hospital. We studied physical and psychological manifestations, stressful life events and, psychiatric diagnosis. The chi-squared test to determine association between anxiety, depressive symptoms and the otorhinolaryngologic symptoms were used. Result: The motive of otorhinolaryngology consultation was ear pain, sore throat, partial deafness, tinnitus and sensation of a foreign body in the throat. The physical examination was negative in 73,2% of the patients. The majority of patients had psychiatrics manifestations and the depressive symptoms and anxiety predominated, which was associated with the ear pain and sore throat. More than half of patients experienced several stressful life events. Conclusions: The mental health problems are frequents in otorhinolaryngology patients without organic apparent disease.

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“…A total of 24 of the indoor air pollution research articles described exposure to dust. For example, dust was noted as a trigger for allergic rhinitis (Adegbiji et al, 2018) and house dust/dust mite exposure was associated with asthma (Bardei et al, 2016;Flatin et al, 2018). Particulate matter was evaluated in 24 of the indoor air pollution research studies, most focusing on PM10 (Abou-Khadra, 2013;Ibhafidon et al, 2014;Makamure et al, 2016;Jafta et al, 2017;Nkhama et al, 2017;Nkosi et al, 2017;Mentz et al, 2018) and PM2.5 exposures (Oluwole et al, 2013;Chafe et al, 2014;Ibhafidon et al, 2014;Dutta et al, 2017;Lacey et al, 2017;Lin et al, 2017a;Malley et al, 2017;Nkhama et al, 2017;Wylie et al, 2017a;Wylie et al, 2017b;Mentz et al, 2018).…”

Section: Exposures Measuredmentioning

confidence: 99%

Environmental Health Research in Africa: Important Progress and Promising Opportunities

Joubert

Mantooth²,

McAllister

2020

Front. Genet.

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The World Health Organization in 2016 estimated that over 20% of the global disease burden and deaths were attributed to modifiable environmental factors. However, data clearly characterizing the impact of environmental exposures and health endpoints in African populations is limited. To describe recent progress and identify important research gaps, we reviewed literature on environmental health research in African populations over the last decade, as well as research incorporating both genomic and environmental factors. We queried PubMed for peer-reviewed research articles, reviews, or books examining environmental exposures and health outcomes in human populations in Africa. Searches utilized medical subheading (MeSH) terms for environmental exposure categories listed in the March 2018 US National Report on Human Exposure to Environmental Chemicals, which includes chemicals with worldwide distributions. Our search strategy retrieved 540 relevant publications, with studies evaluating health impacts of ambient air pollution (n=105), indoor air pollution (n = 166), heavy metals (n = 130), pesticides (n = 95), dietary mold (n = 61), indoor mold (n = 9), per-and polyfluoroalkyl substances (PFASs, n = 0), electronic waste (n = 9), environmental phenols (n = 4), flame retardants (n = 8), and phthalates (n = 3), where publications could belong to more than one exposure category. Only 23 publications characterized both environmental and genomic risk factors. Cardiovascular and respiratory health endpoints impacted by air pollution were comparable to observations in other countries. Air pollution exposures unique to Africa and some other resource limited settings were dust and specific occupational exposures. Literature describing harmful health effects of metals, pesticides, and dietary mold represented a context unique to Africa. Studies of exposures to phthalates, PFASs, phenols, and flame retardants were very limited. These results underscore the need for further focus on current and emerging environmental and chemical health risks as well as better integration of genomic and environmental factors in African research studies. Environmental exposures with distinct routes of exposure, unique co-exposures and co-morbidities, combined with the extensive genomic diversity in Africa may lead to the identification of novel mechanisms underlying complex disease and promising potential for translation to global public health.

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Pattern of allergic rhinitis among children in Ekiti, Nigeria

Cited by 18 publications

References 36 publications

Expression and clinical significance of VCAM-1, IL-6, and IL-17A in patients with allergic rhinitis

Expression and clinical significance of VCAM-1, IL-6, and IL-17A in patients with allergic rhinitis

Factores psicosociales en pacientes de un servicio de otorrinolaringología

Environmental Health Research in Africa: Important Progress and Promising Opportunities

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