Patient survival, predictive factors and disease course of severe sepsis in Czech intensive care units: A multicentre, retrospective, observational study

Uvizl, Radovan; Adamus, Milan; Černý, V.; Dušek, Ladislav; Jarkovský, Jiří; Šrámek, Vladimír; Matějovič, Martin; Štourač, Petr; Kula, R; Maláska, Jan; Ševčík, Pavel

doi:10.5507/bp.2015.052

Cited by 13 publications

(14 citation statements)

References 28 publications

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“…Common themes that emerged from this ILR were: First, implementing the SSC guidelines can decrease the mortality rate among adult patients with sepsis and SS in ICUs; this corresponds to the findings of Lefrant et al [37], Leisman et al [38], Patel et al [33], Pestana et al [21], Cardoso et al [35], Memon et al [39], Sánchez et al [41], Thompson et al [42], van Zanten et al [43], and Levy et al [12]. The second emerged theme was that implementing certain selected guidelines, such as collecting blood cultures and administering broad-spectrum antibiotics and vasopressors can also reduce the mortality rate among adult ICU patients, which was consistent with the findings of Uvizl et al [44] and Ferrer et al There are some limitations of the reviewed studies. Out of the 16 eligible articles, six research articles were descriptive in nature, while the remaining ten research articles used a quasi-experimental design.…”

Section: Discussionsupporting

confidence: 72%

“…However, the sample size was small in the observational study of Pestana et al [21], which may limit its generalizability. The studies of van Zanten et al [43], Thompson et al [42], Uvizl et al [44], Sánchez et al [41], and Leisman et al [38], recruited large numbers of participants. Moreover, the studies of Ferrer et al [45], Castellanos-Ortega et al [32], Patel et al [33], Shiramizo et al [34], Thompson et al [42], Chou et al [20], and Herrán-Monge et al [36] used convenient samples of patients, which might have carried a risk of sampling bias [46].…”

Section: Discussionmentioning

confidence: 99%

“…Two studies investigated the effect of implementing certain practices selected from the SSC guidelines, such as the administration of antibiotics, which was found to decrease the mortality rate [44]…”

Section: Certain Selected Guidelines and Patient Mortalitymentioning

confidence: 99%

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Implementing Surviving Sepsis Campaign Guidelines and Mortality of Adult Patients in Intensive Care Units: An Integrative Review

Omar¹,

Khalaf²,

Alshraideh³

2019

OJN

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Background: Sepsis is a common dangerous body response to infection that can deteriorate into septic shock. Both sepsis and septic shock require early and timely managed care, which can be implemented by using the Surviving Sepsis Campaign (SSC) guidelines for management of sepsis and septic shock. The purpose of this study was to examine the literature related to the effect of implementing SSC guidelines for management of sepsis and septic shock on adult patients' mortality rate in Intensive Care Units (ICUs). Methods: The method of Whittemore and Knafl was used to guide this integrative literature review. The literature search revealed 16 eligible quantitative research studies between 2004 and 2018. The quality of methods used in the included articles was assessed and data were analyzed. Results: Results showed that implementing SSC guidelines reduced the mortality rate among adult patients in ICUs. In addition, implementing selected practices from SSC guidelines, such as collecting blood cultures and administration of a broad-spectrum antibiotic and vasopressors were found to decrease the mortality rate among adult patients in ICUs. The SSC guidelines need to be taught to nurses and nursing students to increase their awareness and capability of implementing these guidelines in clinical practice.

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Section: Discussionsupporting

confidence: 72%

Section: Discussionmentioning

confidence: 99%

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Implementing Surviving Sepsis Campaign Guidelines and Mortality of Adult Patients in Intensive Care Units: An Integrative Review

Omar¹,

Khalaf²,

Alshraideh³

2019

OJN

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“…Trauma that is associated with high mortality is considered to be one of the leading causes of death in young people 1. Death in trauma patients often results from the rapid evolution and deterioration of secondary complications such as shock and uncontrolled hemorrhage 2.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the clinical effect of small-volume resuscitation on uncontrolled hemorrhagic shock in emergency

Zhao

Feng

et al. 2017

TCRM

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ObjectiveThe objective of the present study was to explore the resuscitative effect of small-volume resuscitation on uncontrolled hemorrhagic shock in emergency.MethodsIn this study, the resuscitative effects in 200 trauma patients with uncontrolled hemorrhagic shock in emergency were studied. Half of these patients were infused with hypertonic/hyperoncotic fluid (small-volume resuscitation group, n=100), whereas the rest were infused with Hespan and lactated Ringer’s solution (conventional fluid resuscitation group, n=100). The changes in hemodynamics, coagulation function, blood biochemistry, blood hematology, and the average infusion volume in both the groups were comparatively studied.ResultsIt was found that the hemodynamics were improved in both the groups after resuscitation. Interestingly, compared with trauma patients infused with Hespan and lactated Ringer’s solution, the growth rate, range, and time duration of the mean arterial pressure of the patients in small-volume resuscitation group increased significantly, and the shock index decreased progressively; in the 60th min after the resuscitation, blood index including hemoglobin, hematocrit, red blood cells, white blood cells, and platelet declined, whereas prothrombin time and activated partial thromboplastin time were prolonged in both the groups, but these changes were less obvious in the small-volume group. In addition, the average infusion volume of patients in the small-volume group was less than that of patients in conventional fluid resuscitation group.ConclusionFeatured with small infusion volume and less influence to coagulation function and homeostasis of human body, small-volume resuscitation possesses a significantly higher resuscitative effect. Therefore, trauma patients may have a better chance to maintain the hemodynamic stability and the survival rate, or recovery speed will be increased when traditional aggressive fluid resuscitation is replaced by small-volume resuscitation.

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“…2 ), leading to a clinically more severe course of lung inflammation, especially with frequent complications such as pleural effusions, empyema, acute respiratory distress syndrome (ARDS), septic shock and multiple organ failure 3 . Recent data show that the most frequently isolated etiological agents causing HAP are Klebsiella pneumoniae, Pseudomonas aeruginosa, Burkholderia cepacia complex and Escherichia coli 4 .…”

Section: Introductionmentioning

confidence: 99%

Management of mechanical ventilation in patients with hospital-acquired pneumonia: A retrospective, observational study

Uvizl¹,

Herkel²,

Langová³

et al. 2018

BIOMED PAP

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Patient survival, predictive factors and disease course of severe sepsis in Czech intensive care units: A multicentre, retrospective, observational study

Cited by 13 publications

References 28 publications

Implementing Surviving Sepsis Campaign Guidelines and Mortality of Adult Patients in Intensive Care Units: An Integrative Review

Implementing Surviving Sepsis Campaign Guidelines and Mortality of Adult Patients in Intensive Care Units: An Integrative Review

Evaluation of the clinical effect of small-volume resuscitation on uncontrolled hemorrhagic shock in emergency

Management of mechanical ventilation in patients with hospital-acquired pneumonia: A retrospective, observational study

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