Patient’s Knowledge and Use of Oral Non-Steroidal Anti-Inflammatory Drugs in a Rheumatology Clinic

Arain, Abeer; Rasheed, Mehmoodur; Sallam, Nader; Sarwar, Zoona; Khan, M.G. Irfan Ahmed

doi:10.17161/kjm.v12i4.13260

Cited by 9 publications

(13 citation statements)

References 16 publications

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“…In this sense, we can say that illiterate consumers in Brazil have no power of choice at the point of purchase when buying an OTC drug and can be considered “at-risk consumers” as argued by Pechmann et al (2011). Also, these results complement the findings of previous studies conducted in Europe (Sørensen et al , 2015) and the USA (Arain et al , 2019) and reinforce the findings of previous research conducted in developing countries such as South Africa (Kapp et al , 2020) and Saudi Arabia (AbuAlreesh and Alburikan, 2019).…”

Section: Discussionsupporting

confidence: 84%

“…The use of these medications is a concern in both developed and developing countries. In a study conducted in the USA with 400 participants to evaluate their knowledge of OTC anti-inflammatory drugs, the authors found that almost a third of the them were unaware of the contraindication of the medication, that more than 50% denied having any discussion of OTC medications with their providers and that two-thirds of the respondents reported seeing only the medication packaging for determining the dose (Arain et al , 2019). However, direct-to-consumer (DTC) advertising usually does not provide enough information about therapeutic alternatives, efficacy, costs and risks, and the OTC drug label is the primary means through which instructions for safe and effective use are conveyed to consumers (Cohen et al , 2020).…”

Section: Introductionmentioning

confidence: 99%

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Vulnerability of poorly literate adult consumers regarding over-the-counter drugs

Bernardes

Mattoso

Bouzada

et al. 2020

IJPHM

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Purpose This study aims at verifying the impact of literacy on over-the-counter (OTC) drug consumer vulnerability as evaluated by health literacy and label comprehension. Design/methodology/approach The item response theory (IRT) was used to estimate the health literacy of two groups and the two-way analysis of variance tests was used to test the hypotheses for the existence of mean differences between the two populations. The convenience sample involved 188 OTC consumers: 94 (50%) poorly literate and 94 (50%) university students/graduates. Findings University consumers/graduates have a level of health literacy and label comprehension that is superior to those presented by poor literate consumers. Also, age does not influence the level of health literacy by OTC drug users but has a significant impact on the understanding of OTC drug labels. Finally, the level of schooling and the “age group,” simultaneously, does not impact the understanding of OTC drug labels or health literacy. Research limitations/implications This study has added in the field of knowledge by investigating the behavior of poor literate consumers in Brazil, a developing country. The results may be relevant to Marketing professionals, especially those in the pharmaceutical industry, and to police makers, as they help identify the main problems faced by poorly literate consumers. Practical implications It is necessary to raise awareness of the dangers of self-medication and wrong use of medications, mainly focused on people with low literacy. As a suggestion, a simple glossary presented along with the label could provide explanations of scientific terms, thus increasing health literacy and reducing the vulnerability of the consumers. Social implications This study showed that when using common words such as gastritis to define a health problem, there is a higher degree of correctness. These results suggest the adoption of a more straightforward language and more precise explanations. By doing that, the pharmaceutical industry and policymakers will improve their social impact by increasing consumer power and taking care of the health of the most vulnerable population: the illiterate people. Originality/value This study contributes to the international literature, as it enhances and clarifies the knowledge about the customers’ power and vulnerability in developing countries. It fills a gap by evaluating label comprehension and heath literacy at the same time, giving an academic contribution for pharmaceutical consumers’ studies.

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Section: Discussionsupporting

confidence: 84%

Section: Introductionmentioning

confidence: 99%

Vulnerability of poorly literate adult consumers regarding over-the-counter drugs

Bernardes

Mattoso

Bouzada

et al. 2020

IJPHM

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“…In addition, analgesics can lead to side effects that affect the health of the consumer. In the aforementioned study, one third of the population was unaware of contraindications associated with analgesics [ 24 ]. After analgesics, antitussives and common cold drugs were most commonly consumed by our subjects, which is different to the results published by other authors, who reported that analgesics are the most consumed, followed by antipyretics and antibiotics [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

Consumption of over-the-Counter Drugs: Prevalence and Type of Drugs

Sánchez-Sánchez

Fernández-Cerezo²,

Díaz-Jiménez

et al. 2021

IJERPH

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Recently, there has been an increase in the use of over-the-counter (OTC) drugs. The consumption of these medicines can be unsafe, as incorrect self-diagnosis or the ingestion of inappropriate doses can lead to side effects and the occurrence of adverse reactions and drug–drug interactions. A cross-sectional descriptive observational study was carried out, targeting the entire Spanish population by using an online questionnaire. The results showed that 78.9% of the subjects had previously taken or were currently taking OTC drugs. This consumption decreased as the age of the subjects increased, with a prevalence of 36.4% of subjects aged ≥71 taking OTC drugs. Analgesics were the most consumed OTC drugs (49.1%) especially in women, youngsters with non-formal educational qualifications, and individuals of a low–medium socioeconomic level residing in urban areas. Measures should be implemented to optimize the safe use of OTC drugs in order to avoid the occurrence of secondary events associated with the lack of knowledge related to their the usage.

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“…One of these factors could be the lack of knowledge in NSAID users about their AEs and contraindications. In a study of over-the-counter (OTC) NSAID users surveyed at a rheumatology clinic, one-third were unaware of their contraindications [ 41 ]. Similar reports of the lack of patient knowledge about NSAIDs-related AEs have been published as well [ 42 , 43 ].…”

Section: Discussionmentioning

confidence: 99%

A Machine Learning Approach to Identify Predictors of Potentially Inappropriate Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Use in Older Adults with Osteoarthritis

Patel

Ladani

Sambamoorthi

et al. 2020

IJERPH

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Evidence from some studies suggest that osteoarthritis (OA) patients are often prescribed non-steroidal anti-inflammatory drugs (NSAIDs) that are not in accordance with their cardiovascular (CV) or gastrointestinal (GI) risk profiles. However, no such study has been carried out in the United States. Therefore, we sought to examine the prevalence and predictors of potentially inappropriate NSAIDs use in older adults (age > 65) with OA using machine learning with real-world data from Optum De-identified Clinformatics® Data Mart. We identified a retrospective cohort of eligible individuals using data from 2015 (baseline) and 2016 (follow-up). Potentially inappropriate NSAIDs use was identified using the type (COX-2 selective vs. non-selective) and length of NSAIDs use and an individual’s CV and GI risk. Predictors of potentially inappropriate NSAIDs use were identified using eXtreme Gradient Boosting. Our study cohort comprised of 44,990 individuals (mean age 75.9 years). We found that 12.8% individuals had potentially inappropriate NSAIDs use, but the rate was disproportionately higher (44.5%) in individuals at low CV/high GI risk. Longer duration of NSAIDs use during baseline (AOR 1.02; 95% CI:1.02–1.02 for both non-selective and selective NSAIDs) was associated with a higher risk of potentially inappropriate NSAIDs use. Additionally, individuals with low CV/high GI (AOR 1.34; 95% CI:1.20–1.50) and high CV/low GI risk (AOR 1.61; 95% CI:1.34–1.93) were also more likely to have potentially inappropriate NSAIDs use. Heightened surveillance of older adults with OA requiring NSAIDs is warranted.

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Patient’s Knowledge and Use of Oral Non-Steroidal Anti-Inflammatory Drugs in a Rheumatology Clinic

Cited by 9 publications

References 16 publications

Vulnerability of poorly literate adult consumers regarding over-the-counter drugs

Vulnerability of poorly literate adult consumers regarding over-the-counter drugs

Consumption of over-the-Counter Drugs: Prevalence and Type of Drugs

A Machine Learning Approach to Identify Predictors of Potentially Inappropriate Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Use in Older Adults with Osteoarthritis

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