Pathways and molecules for overcoming immunotolerance in metastatic gastrointestinal tumors
Qixin Gan,
Yue Li,
Yuejun Li
et al.
Abstract:Worldwide, gastrointestinal (GI) cancer is recognized as one of the leading malignancies diagnosed in both genders, with mortality largely attributed to metastatic dissemination. It has been identified that in GI cancer, a variety of signaling pathways and key molecules are modified, leading to the emergence of an immunotolerance phenotype. Such modifications are pivotal in the malignancy’s evasion of immune detection. Thus, a thorough analysis of the pathways and molecules contributing to GI cancer’s immunoto… Show more
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