Pathologies rhumatologiques et hémoglobinopathies à Ouagadougou (Burkina Faso)

Ouédraogo, Dieu-Donné; Nacoulma, E. W. C.; Kafando, Eléonore; Ouédraogo, A.; Tiéno, H.; Koulidiaty, J.; Drabo, Joseph

doi:10.1007/s13149-010-0052-1

Cited by 6 publications

(7 citation statements)

References 7 publications

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“…The prevalence of antimalarial self-medication reported in this study is lower than 93.1% previously reported in Benin in children under five years [14] and (89.6%) in Kisangani [15] and (99%) in Lubumbashi [5] in Democratic Republic of Congo. The reported prevalence in this study is similar to 72.7% observed in a survey conducted in Burkina Faso in 2014 [16]. Lower prevalence were observed among children under five in Ghana (16.8%) [17] and in Togo (42%) [18].…”

Section: Prevalence Of Antimalarial Selfmedication In Householdssupporting

confidence: 87%

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Prevalence and Determinants of Antimalarial Self-medication in Southern Benin

Aguèh

Badet

Jérôme

et al. 2016

IJTDH

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Aims: To determine the prevalence of antimalarial self-medication and identify its determinants in Comé, Southern Benin households. Study Design: Cross-sectional community based study. Place and Duration of Study: Benin southern setting, from April to July 2015. Methodology: It was a cross-sectional study conducted from 1 st to 14 th July 2015 which involved 480 households randomly selected. Data on socioeconomic and demographic factors, the use of

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Section: Prevalence Of Antimalarial Selfmedication In Householdssupporting

confidence: 87%

“…Indeed, the study previously carried out in Benin involved children under 5 years [13] as well as the Ghana study [17] while the present study concerned adults. The study in Burkina Faso was carried out in hospital [16].…”

Section: Prevalence Of Antimalarial Selfmedication In Householdsmentioning

confidence: 99%

Prevalence and Determinants of Antimalarial Self-medication in Southern Benin

Aguèh

Badet

Jérôme

et al. 2016

IJTDH

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“…La drépanocytose, la consommation d'alcool et le VIH étaient les principaux facteurs favorisants. Les hémoglobinopathies constituent le premier facteur favorisant des ONATF en Afrique Noire avec comme principale pourvoyeuse la forme SC [6,10,24]. La responsabilité des autres formes d'hémoglobinopathies (AS, AC) est discutée [11,19,24].…”

Section: Discussionunclassified

“…Les hémoglobinopathies constituent le premier facteur favorisant des ONATF en Afrique Noire avec comme principale pourvoyeuse la forme SC [6,10,24]. La responsabilité des autres formes d'hémoglobinopathies (AS, AC) est discutée [11,19,24]. Elles surviennent à un âge précoce [8].…”

Section: Discussionunclassified

Ostéonécrose aseptique de la tête fémorale en milieu rhumatologique au Togo

Kakpovi,

Fianyo,

Zabsonré/Tiendrébéogo

et al. 2022

Rhum Afr Franc

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Introduction: déterminer le profil épidémiologique et sémiologique de l’ostéonécrose aseptique de la tête fémorale (ONATF) ainsi que les principaux facteurs favorisants en milieu rhumatologique au Togo.Matériels et méthodes: il s’est agi d’une étude rétrospective a visée descriptive menée d’octobre 1989 à juillet 2016 dans le service de rhumatologie du CHU- Sylvanus Olympio de Lomé. Ont été inclus dans notre étude tous les patients ayant moins de 16 ans et dont le motif de consultation était rhumatologique.Résultats: deux cent quarante-et-un patients avaient une ONATF. Ils se répartissaient en 56,02% de femmes et 43,98% d’hommes. L’âge moyen des patients était de 39 ans ± 14 ans avec des extrêmes allant de 9 à 80 ans. La durée d’évolution moyenne de la maladie était de 3,36 ans ± 4,6 ans avec des extrêmes de 11 jours et 27 ans. La douleur de la hanche était le principal motif de consultation. Elle siégeait à l’aine (165 cas ; 68,46%), au grand trochanter (108 cas ; 44,81%), à la fesse (47 cas ; 19,50%). La douleur était projetée à la cuisse chez 86 patients (35,68%). La marche était douloureuse chez 207 patients (85,9%) et associée à une boiterie chez 199 patients (82,57%). Selon la classification d’Arlet et Ficat, l’image radiographique des ONATF au diagnostic était au stade II (57 cas ; 23,65%), austade III (99 cas ; 41,08%) et au stade IV (85 cas ; 35,27%). L’atteinte était unilatérale (186 cas ; 77,17%) et bilatérale (55 cas ; 22,83%). Les principaux facteurs favorisants de l’ONATF retrouvés étaient : une hémoglobinopathie (79 cas ; 32,8%), l’éthylisme chronique (68 cas ; 28,2%) et l’infection au VIH (20 cas ; 8,3%).Conclusion: outre les formes évoluées dues au retard diagnostique, l’ONATF ne revêt pas de particularités sémiologiques. La drépanocytose, la consommation d’alcool et le VIH restent les principaux facteurs favorisants.

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“…(Asteraceae) (Figure 1). In Burkina Faso traditional medicine, these plants are used as depurative, diuretic, and to treat liver disorders (Nacoulma Ouedraogo, 1996).…”

Section: Introductionmentioning

confidence: 99%

Polyphenol content, antioxidant and antiproliferative effects of a plant mixture composed of four medicinal plants with hepatoprotective potential

Boly,

Kindo,

Traore

et al. 2023

Afr. J. Pharm. Pharmacol.

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Reactive oxygen species (ROS), known as normal by-products of various cellular processes, are involved in several human diseases, including cancer and liver diseases. The present study aimed to (i) determine the polyphenol contents, (ii) assess the antioxidant, and (iii) antiproliferative effects of a mixture composed of Balanites aegyptiaca, Calotropis procera, Cochlospermum tinctorium, and Acanthospermum hispidum. These plants are reported to elicit various properties, including antioxidant, hepatoprotective, and anticancer. The phytochemicals were screened qualitatively, and Folin and Ciocalteu as well as aluminium chloride were used as reagents, to measure the total phenolics (TPC) and flavonoids (TFC), respectively. The antioxidant assay used four assays: DPPH, ABTS, FRAP, and LPO. The antiproliferative effect of the mixture was investigated on the human hepatocarcinoma cell line Hep3B. The phytochemical screening revealed the presence of saponins, flavonoids, tannins, sterols, coumarins, and triterpenes. The mixture seems richer in total phenolics (208.81 ± 1.13 mg GAE/g extract) than flavonoids (10.74 ± 1.44 mg QE/g extract). Regarding the radical scavenging activity, the mixture significantly inhibited ABTS radicals with an IC 50 value of 11.61 ± 0.0006 µg/ml. Moreover, it was potent in reducing ferric iron (133.06 mol AAE/g) and inhibiting lipid peroxidation (inhibition percentage equal to 56.39%). The mixture showed a considerable antiproliferative effect against the Hep3B cells with an IC50 value of 1.1 ± 0.75 µg/mL The beneficial effects attributed to the mixture may be explained by the presence of phenolics known for their potent antioxidant properties. The study findings suggest a promising synergistic plant combination for protecting the liver from oxidative stress and cancer. However, more detailed studies are needed to identify and confirm the antioxidant and antiproliferative mechanisms of action.

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Pathologies rhumatologiques et hémoglobinopathies à Ouagadougou (Burkina Faso)

Cited by 6 publications

References 7 publications

Prevalence and Determinants of Antimalarial Self-medication in Southern Benin

Prevalence and Determinants of Antimalarial Self-medication in Southern Benin

Ostéonécrose aseptique de la tête fémorale en milieu rhumatologique au Togo

Polyphenol content, antioxidant and antiproliferative effects of a plant mixture composed of four medicinal plants with hepatoprotective potential

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