Infectious Disease Clinics of North America volume 18, issue 3, P467-511 2004 DOI: 10.1016/j.idc.2004.04.003 View full text
Keith S Kaye, John J Engemann, Henry S Fraimow, Elias Abrutyn

Abstract: Resistance to antimicrobial drugs is increasing at an alarming rate among both gram-positive and gram-negative bacteria. Traditionally, bacteria resistant to multiple antimicrobial agents have been restricted to the nosocomial environment. A disturbing trend has been the recent emergence and spread of resistant pathogens and resistance traits in nursing homes, the community, as well as in hospitals. This article reviews the epidemiology, molecular mechanisms of resistance, and treatment options for pathogens r…

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