Pathogenesis of Hypertension in Glomerular Disease

Selective Increase of the Contractile Response to Endothelin-1 in Subcutaneous Arteries from Patients with Essential Hypertension

“…There is also some evidence that any familial tendency to hypertension will increase the prevalence of renal failure in patients with primary renal disorders [176] or with diabetes [177]. There is little evidence from randomised trials in hypertensive patients to show that treatment modifies the slight risk of developing renal failure, but more compelling evidence that blood pressure control will slow progression in patients with renal failure [178].…”