Pathogenesis of Encephalitis Occurring With Vaccination, Variola and Measles

The Post-Infection Encephalitides

“…While vaccinia virus was occasionally isolated from the brain or c.s.f. The final hypothesis, and one that has gained favour from recent experimental work, was advanced by Glan7mann (1927) d and strongly supported by Finley (1938)**. An alternative hypothesis that vaccinial infection exposes the nervous system to invasion by a second virus received no support from experiments in which poliomyelitis and vaccinia were injected into the same animal (Hurst & Fairbrother, 1931)/, nor was a second virus ever isolated to substantiate the view that a latent infection might have been activated by vaccinia.…”

The Post-Infection Encephalitides

“…While vaccinia virus was occasionally isolated from the brain or c.s.f. The final hypothesis, and one that has gained favour from recent experimental work, was advanced by Glan7mann (1927) d and strongly supported by Finley (1938)**. An alternative hypothesis that vaccinial infection exposes the nervous system to invasion by a second virus received no support from experiments in which poliomyelitis and vaccinia were injected into the same animal (Hurst & Fairbrother, 1931)/, nor was a second virus ever isolated to substantiate the view that a latent infection might have been activated by vaccinia.…”

Leukocyte Migration Inhibition by Brain Tissue Antigens in Acute Inflammatory Diseases of the Nervous System

“…It was suggested decades ago that acute inflammatory diseases (AID) of the nervous system (NS), characterized by demyelination, were of an allergic nature (6,11,13,22). The idea that diseases of this kind may be brought about by sensitization with nervous tissue (NT) was supported by experiences with experimental allergic encephalitis and experimental allergic neuritis in animals (16,18,21,25).…”

The Post-Infection Encephalitides

“…While vaccinia virus was occasionally isolated from the brain or c.s.f. The final hypothesis, and one that has gained favour from recent experimental work, was advanced by Glan7mann (1927) d and strongly supported by Finley (1938)**. An alternative hypothesis that vaccinial infection exposes the nervous system to invasion by a second virus received no support from experiments in which poliomyelitis and vaccinia were injected into the same animal (Hurst & Fairbrother, 1931)/, nor was a second virus ever isolated to substantiate the view that a latent infection might have been activated by vaccinia.…”

Leukocyte Migration Inhibition by Brain Tissue Antigens in Acute Inflammatory Diseases of the Nervous System

“…It was suggested decades ago that acute inflammatory diseases (AID) of the nervous system (NS), characterized by demyelination, were of an allergic nature (6,11,13,22). The idea that diseases of this kind may be brought about by sensitization with nervous tissue (NT) was supported by experiences with experimental allergic encephalitis and experimental allergic neuritis in animals (16,18,21,25).…”

The Post-Infection Encephalitides

“…While vaccinia virus was occasionally isolated from the brain or c.s.f. The final hypothesis, and one that has gained favour from recent experimental work, was advanced by Glan7mann (1927) d and strongly supported by Finley (1938)**. An alternative hypothesis that vaccinial infection exposes the nervous system to invasion by a second virus received no support from experiments in which poliomyelitis and vaccinia were injected into the same animal (Hurst & Fairbrother, 1931)/, nor was a second virus ever isolated to substantiate the view that a latent infection might have been activated by vaccinia.…”

Leukocyte Migration Inhibition by Brain Tissue Antigens in Acute Inflammatory Diseases of the Nervous System

“…It was suggested decades ago that acute inflammatory diseases (AID) of the nervous system (NS), characterized by demyelination, were of an allergic nature (6,11,13,22). The idea that diseases of this kind may be brought about by sensitization with nervous tissue (NT) was supported by experiences with experimental allergic encephalitis and experimental allergic neuritis in animals (16,18,21,25).…”