J. Neurosci. Res. volume 87, issue 1, P1-11 2009 DOI: 10.1002/jnr.21823 View full text
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Angelos G. Kolias, Jon Sen, Antonio Belli

Abstract: Cerebral vasospasm is a potentially incapacitating or lethal complication in patients with aneurysmal subarachnoid hemorrhage (SAH). The development of effective preventative and therapeutic interventions has been largely hindered by the fact that the underlying pathogenic mechanisms of cerebral vasospasm remain poorly understood. However, intensive research during the last 3 decades has identified certain mechanisms that possibly play a role in its development. Experimental data suggest that calcium-dependent…

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