Pasteurella multocida Endocarditis: Report of a Case and Review of the Literature

Genné, Daniel; Siegrist, Hans H.; Monnier, Patrick; Nobel, Monica; Humair, L; Torrenté, Antoine de

doi:10.3109/00365549609027158

Cited by 24 publications

(16 citation statements)

References 15 publications

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“…septica between cats and babies (2,18). As in the present case, a significant proproportion of P. multocida infections in humans are associated with animal exposure without any injury (3,10,13,16,19). Moreover, some systemic infections can even not be associated with any animal exposure at all (7,16).…”

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confidence: 50%

Molecular Identification and Epidemiological Tracing of Pasteurella multocida Meningitis in a Baby

et al. 2000

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We report a case of Pasteurella multocida meningitis in a 1-month-old baby exposed to close contact with two dogs and a cat but without any known history of injury by these animals. 16S rRNA gene sequencing of the isolate from the baby allowed identification at the subspecies level and pointed to the cat as a possible source of infection. Molecular typing of Pasteurella isolates from the animals, from the baby, and from unrelated animals clearly confirmed that the cat harbored the same P. multocidasubsp. septica strain on its tonsils as the one isolated from the cerebrospinal fluid of the baby. This case stresses the necessity of informing susceptible hosts at risk of contracting zoonotic agents about some basic hygiene rules when keeping pets. In addition, this study illustrates the usefulness of molecular methods for identification and epidemiological tracing ofPasteurella isolates.

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confidence: 50%

Molecular Identification and Epidemiological Tracing of Pasteurella multocida Meningitis in a Baby

et al. 2000

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“…Leukocyte and neutrophil counts are typically high at the infection site, and inflammation develops very rapidly. In more severe cases, pasteurellosis can rapidly progress to bacteremia (fulminant sepsis) (41, 161,235,241,251,[256][257][258][259][260][261][262][263][264][265][266] and other complications such as osteomyelitis (inflammation of the bone) (155,165,(267)(268)(269), endocarditis (inflammation of the heart) (256,263,(270)(271)(272)(273)(274)(275)(276)(277)(278)(279)(280)(281)(282)(283)(284)(285), and meningitis (inflammation of the meninges) (53, 90, 159, 163, 165, 264, 286-293).…”

Section: Pasteurella and Other Pasteurellaceae Diseases In Humans Pasmentioning

confidence: 99%

Pasteurella multocida: from Zoonosis to Cellular Microbiology

2013

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SUMMARY In a world where most emerging and reemerging infectious diseases are zoonotic in nature and our contacts with both domestic and wild animals abound, there is growing awareness of the potential for human acquisition of animal diseases. Like other Pasteurellaceae , Pasteurella species are highly prevalent among animal populations, where they are often found as part of the normal microbiota of the oral, nasopharyngeal, and upper respiratory tracts. Many Pasteurella species are opportunistic pathogens that can cause endemic disease and are associated increasingly with epizootic outbreaks. Zoonotic transmission to humans usually occurs through animal bites or contact with nasal secretions, with P. multocida being the most prevalent isolate observed in human infections. Here we review recent comparative genomics and molecular pathogenesis studies that have advanced our understanding of the multiple virulence mechanisms employed by Pasteurella species to establish acute and chronic infections. We also summarize efforts being explored to enhance our ability to rapidly and accurately identify and distinguish among clinical isolates and to control pasteurellosis by improved development of new vaccines and treatment regimens.

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“…The present case stresses the danger of casual contact between humans and pets. Fortunately, the low number of reported Pasteurella multocida infections suggests that the risk of transmission of this zoonotic agent from domestic animals to humans is probably very low [15]. However, some basic rules of hygiene should be respected when immunocompromised patients, small children, and the elderly come into contact with pets [1].…”

Section: Resultsmentioning

confidence: 99%

Molecular Identification of TEM-1 β-Lactamase in a Pasteurella multocida Isolate of Human Origin

Naas

Benaoudia

Lebrun

et al. 2001

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Two clinical strains of Pasteurella multocida were isolated from an HIV-infected patient who developed arthritis. Strain FB-1, which was isolated from a dog-bite wound, was resistant to narrow-spectrum penicillins. The second strain, FB-2, which was present in blood cultures as well as the dog-bite wound, was susceptible to all beta-lactam agents. Arbitrarily primedpolymerase chain reaction and pulsed-field gel electrophoresis revealed that these two isolates were genetically indistinguishable. 16S rDNA gene sequencing facilitated identification at the subspecies level. Amoxicillin resistance determinant was located on a highly unstable 4.3-kb plasmid, pFAB-1. Isoelectrofocusing and polymerase chain reaction amplification followed by sequencing revealed the presence of a pI 5.4 TEM-1 beta-lactamase. This description is the first of a TEM-1 Beta-lactamase' in a Pasteurella multocida strain of human origin.

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Pasteurella multocida Endocarditis: Report of a Case and Review of the Literature

Abstract: We report on a cirrhotic patient who presented with an aortic valve endocarditis due to Pasteurella multocida. This disease entity is rare and we take this opportunity to review the 6 cases published to date.

Cited by 24 publications

References 15 publications

Molecular Identification and Epidemiological Tracing of Pasteurella multocida Meningitis in a Baby

Molecular Identification and Epidemiological Tracing of Pasteurella multocida Meningitis in a Baby

Pasteurella multocida: from Zoonosis to Cellular Microbiology

Molecular Identification of TEM-1 β-Lactamase in a Pasteurella multocida Isolate of Human Origin

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