Partition behavior of hydrophilic diols in an ethanol/ammonium sulfate salting‐out extraction system

Abstract

It is important to investigate the partition behavior of hydrophilic alcohols at different process parameters in order to have a deep understanding of the salting-out extraction technique and to design suitable downstream processes. First, phase diagram data of ethanol/ammonium sulfate at 293.15 K were obtained, and the reliability of binodal curve and tie line data were proved by Merchuk, Othmer-Tobias, and Bancroft equations, respectively. Then, the partition behavior of five short-chain diols was studied. For different tie lines, the partition coefficient changed linearly with an increase in tie line length. The concentration of diols also had a significant effect on the partition behavior due to the similarity between diols and ethanol. Further, the effect of temperature was increased as the hydrophobicity of the diols increased, and the partition behavior of diols was correlated with their hydrophobicity, implying that the solutes with higher hydrophobicity could be extracted more effectively. These findings are useful for designing an economic and efficient salting-out extraction process for diverse products.

Salts and 1‐propanol induced aqueous two‐phase systems: phase separation and application

“…Compared with the more polar extractant ethanol, 1‐propanol showed the stronger salting‐out effect by all the electrolytes investigated in this study (Fig. ) . With the increase of salt concentration in the saline aqueous phase, the solubility of 1‐propanol decreased more sharply than that of ethanol.…”

Ethanol/ammonium sulfate ultrasonic‐assisted liquid–liquid extraction of flavonoids from Tibetan Sea‐buckthorn fruit

“…ATPSs are usually formed when two polymers or one polymer and an appropriate salt are combined in a certain ratio. Recently, a novel type of ATPS based on alcohol+salt combinations or ionic liquids has been developed, which facilitates phase separation, increases the extraction yields, decreases the environmental pollution during solvent recycling, and decreases the production cost (Chong et al, 2020; Fu, Dai, et al, 2015; Fu, Yang, & Xiu, 2015; Li et al, 2017; Liu et al, 2013; Wang et al, 2015).…”

Protein purification of Arthrospira platensis using aqueous two-phase system composed of polyethylene glycol and potassium phosphate/sodium citrate

“…The efficiency of the biomolecule partition, by applying ATPS, can be improved by manipulating parameters, such as ATPS component concentration, pH, and temperature (Raja et al 2011;Fu et al 2015). Obtaining the compound of interest is complex and occurs by hydrophobic interactions and hydrogen bonds between the target molecule and the phase components (Marcos et al 2002).…”