Participation of lectins in crustacean immune system

Sánchez-Salgado, José Luis; Pereyra, Mohamed Alí; Agundis, Concepción; Vivanco-Rojas, Óscar; Sierra-Castillo, Claudia; Alpuche, Juan; Zenteno, Edgar

doi:10.1111/are.13394

Cited by 31 publications

(14 citation statements)

References 69 publications

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“…Genes participating in innate immunity of invertebrates were enriched among the positively selected genes, including lectin, caspase, serine proteinase and AMP. As important pattern recognition receptors (PRRs), the crustacean lectins recognize glycans on the cell surface of invading pathogens and activate a range of immune responses [52]. However, PRRs are also required to promote the normal colonization of gut microbiota [53].…”

Section: Gene Id E Value Nr Annotationmentioning

confidence: 99%

Insights into the strategy of micro-environmental adaptation: Transcriptomic analysis of two alvinocaridid shrimps at a hydrothermal vent

et al. 2020

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Diffusing fluid at a deep-sea hydrothermal vent creates rapid, acute physico-chemical gradients that correlate strongly with the distribution of the vent fauna. Two alvinocaridid shrimps, Alvinocaris longirostris and Shinkaicaris leurokolos occupy distinct microhabitats around these vents and exhibit different thermal preferences. S. leurokolos inhabits the central area closer to the active chimney, while A. longirostris inhabits the peripheral area. In this study, we screened candidate genes that might be involved in niche separation and microhabitat adaptation through comparative transcriptomics. The results showed that among the top 20% of overexpressed genes, gene families related to protein synthesis and structural components were much more abundant in S. leurokolos compared to A. longirostris. Moreover, 15 out of 25 genes involved in cellular carbohydrate metabolism were related to trehalose biosynthesis, versus 1 out of 5 in A. longirostris. Trehalose, a non-reducing disaccharide, is a multifunctional molecule and has been proven to act as a protectant responsible for thermotolerance in Saccharomyces cerevisiae. Putative positively selected genes involved in chitin metabolism and the immune system (lectin, serine protease and antimicrobial peptide) were enriched in S. leurokolos. In particular, one collagen and two serine proteases were found to have experienced strong positive selection. In addition, sulfotransferase-related genes were both overexpressed and positively selected in S. leurokolos. Finally, genes related to structural proteins, immune proteins and protectants were overexpressed or positively selected. These characteristics could represent adaptations of S. leurokolos to its microhabitat, which need to be confirmed by more evidence, such as data from large samples and different development stages of these alvinocaridid shrimps.

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Section: Gene Id E Value Nr Annotationmentioning

confidence: 99%

Insights into the strategy of micro-environmental adaptation: Transcriptomic analysis of two alvinocaridid shrimps at a hydrothermal vent

et al. 2020

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“…Dendritic cells and macrophages recognize microbe-derived molecules (microbe-associated molecular patterns, MAMPs) through pattern recognition receptors (PRRs) expressed on the cell surface or inside the cells. MAMPs include lipopolysaccharides, peptidoglycans, β-1, 3glucans, lectins, and nucleic acids (Kaisho et al, 2004;Cerenius et al, 2010;Smith et al, 2010Smith et al, , 2018Song et al, 2010;Sánchez-Salgado et al, 2017). Including Toll-like receptors (TRLs), 11 types of PRRs have been identified in shrimp (Wang et al, 2013).…”

Section: Shellfish Immune Systemmentioning

confidence: 99%

“…The presence of other types of PRRs, such as NOD-like receptors (NLRs) and RIG-like receptors (RLRs) need to be identified in shrimp and other shellfish species. The interaction between PRRs and MAMPs activates receptor-dependent signalling pathways, which results in innate immune responses: cytokine production and stimulation of phagocytosis, clotting proteins, apoptosis, antimicrobial proteins (AMPs), and the complement system (Kaisho et al, 2004;Cerenius et al, 2010;Smith et al, 2010Smith et al, , 2018Song et al, 2010;Li et al, 2013;Sánchez-Salgado et al, 2017). C-type (Ca 2+ dependent) lectins are most common in shellfish among the lectin groups.…”

Section: Shellfish Immune Systemmentioning

confidence: 99%

“…Innate immune cells recognize microbes via pattern recognition receptors, which leads to the induction of immune responses, and eventually eliminates pathogens. Innate immune responses are directly dependant on the activated status of degradation enzymes, synthetic enzymes of reactive oxygen species, phagocytic cells, clotting proteins, and complement proteins (Tripp, 1974;Bayne, 1983;Gross et al, 1999;Sritunyalucksana et al, 2000;Kimbrell et al, 2001;Pasquier, 2001;Salzet, 2001;Tort et al, 2003;Beutler, 2004;Ausubel, 2005;Magnadottir et al, 2006;Vazquez et al, 2009;Harikrishnan et al, 2011;Ringø et al, 2012Ringø et al, , 2018Chiaramonte et al, 2015;Romo et al, 2015;Song et al, 2015;Sánchez-Salgado et al, 2017;Smith et al, 2018). Generally, LAB affect various species including shellfish by improving their immune status, which leads to a more robust protection against various pathogens (Ige, 2013;Maeda et al, 2014;Merrifield et al, 2014;Vasama et al, 2014;Sha et al, 2016b;Ringø et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

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Lactic Acid Bacteria in Shellfish: Possibilities and Challenges

Ringø

Doan

Lee

et al. 2019

Reviews in Fisheries Science & Aquaculture

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“…Lectins play dynamic role in crustacean immunity and survival by participating in cell-cell interaction, cell-signaling, protein synthesis and pathogen recognition (Denis et al, 2016;Sanchez-Salgado et al, 2017). Crustacean lectins are more dynamic as they participate in humoral defence through recognition and antibacterial activity and cellular defense through encapsulation and phagocytosis (Vazquez et al, 2009;.…”

Section: Introductionmentioning

confidence: 99%