volume 99, issue 1, Pe2-e2 1997
DOI: 10.1542/peds.99.1.e2
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J. S. Greenspan, W. W. Fox, S. D. Rubenstein, M. R. Wolfson, S. S. Spinner, T. H. Shaffer

Abstract: ABSTRACT. Objectives. To demonstrate that a period of partial liquid ventilation (PLV) with perflubron improves pulmonary function, without adverse events, in a select group of critically ill infants receiving extracorporeal life support (ECLS) with a high likelihood of mortality.Methods. This was an open-label, noncontrolled, phase I and II trial of PLV in two infants with congenital diaphragmatic hernia and four infants with acute respiratory distress syndrome (ARDS) who were failing to improve while receiv…

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