Parotid gland surgery: 4‐Year review of 118 cases in an Asian population

Lim, Liangzhong; Chao, Siew Shuen; Goh, Christopher; Ng, Choon Ta; Goh, Yau Hong; Khin, Lay Wai

doi:10.1002/hed.10267

Cited by 25 publications

(19 citation statements)

References 23 publications

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“…In general, is seems that CanAd may not develop in major salivary glands. Cases reported thus far in the major salivary glands (parotid, submandibular) are either not well illustrated or lack immunohistochemistry studies to confirm the diagnosis [25,64,69,[92][93][94][95]. Additional investigation is encouraged.…”

Section: Clinical Informationmentioning

confidence: 99%

Canalicular Adenoma: A Clinicopathologic and Immunohistochemical Analysis of 67 Cases with a Review of the Literature

Thompson

Bauer

Chiosea

et al. 2014

Head and Neck Pathol

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There is a lack of a comprehensive immunohistochemical (IHC) analysis of canalicular adenoma (CanAd), especially when combined with a description of the unique histologic features. Given the usual small biopsies, IHC may be useful in distinguishing CanAd from other tumors in the differential diagnosis. Retrospective. The patients included 54 females and 13 males (4.2:1), aged 43-90 years, with a mean age at presentation of 69.9 years. Clinical presentation was generally a mass (n = 61) slowly increasing in size (mean 38.5 months), affecting the upper lip (n = 46), buccal mucosa (n = 17) or palate (n = 4), involving the right (n = 29), left (n = 24) or midline (n = 9), without any major salivary gland tumors. The tumors ranged in size from 0.2 to 3 cm (mean 1.2 cm). Most tumors were multilobular or bosselated (76 %), often surrounded by a capsule. Histologically, the tumors were characterized by cystic spaces, tumor cords with beading, tubule formation, and by the presence of luminal squamous balls (n = 41). The cells were cuboidal to columnar with stippled chromatin. Mitoses were inconspicuous. A myxoid stroma (n = 64), sclerosis (n = 42), luminal hemorrhage (n = 51), and luminal microliths (calcifications) (n = 33) were characteristic. Nine (13.4 %) were multifocal. CanAd showed the following characteristic immunohistochemistry findings: CK-pan and S100 protein (strong, diffuse reaction); peripheral or luminal GFAP reaction; CK5/6 and p16 luminal squamous ball reaction; SOX10 nuclear reaction; cytoplasmic p63 reaction. CanAd are unique minor salivary gland tumors showing a distinct architecture and phenotype. They predilect to older women, with the majority multilobulated and affecting the upper lip, multifocal in 13 %; no major salivary gland tumors were identified. S100 protein, CK-pan, GFAP and SOX10 are positive, with luminal squamous balls highlighted by CK5/6 or p16.

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Section: Clinical Informationmentioning

confidence: 99%

Canalicular Adenoma: A Clinicopathologic and Immunohistochemical Analysis of 67 Cases with a Review of the Literature

Thompson

Bauer

Chiosea

et al. 2014

Head and Neck Pathol

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“…However, amongst LMs closely associated with the FN, some incidences of FN injury have been reported as much higher than the rate for standard parotid surgery [4][5][6][7][8][9]. This is expected because the LM can involve local soft tissue altering typical anatomy, can completely surround the FN, and can elongate the FN, thus displacing branches of the facial nerve from their typical and expected locations [1].…”

Section: Discussionmentioning

confidence: 94%

“…Rates of short-term, postparotidectomy facial paresis range from 27 to 65%, with rates of permanent paralysis being 4-7% [6][7][8][9]. Intraoperative facial nerve monitoring during parotid surgery allows for early identification of the FN, mapping of its course through the facial region, warning of unexpected stimulation during dissection, and determination of FN prognosis at conclusion of surgery.…”

Section: Introductionmentioning

confidence: 98%

Facial nerve mapping and monitoring in lymphatic malformation surgery

Chiara¹,

Kinney²,

Slimp³

et al. 2009

International Journal of Pediatric Otorhinolaryngology

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“…Ansari et al also reported monomorphic adenomas in the parotid gland, but provided no differentiation between CA and basal cell adenoma [23]. In addition, six of these reports did not provide specific information, such as clinical symptoms, histologic findings, or treatment methods [5,[8][9][10][11][12][13][14][15][16][17][18][19][20][21][22].…”

Section: Discussionmentioning

confidence: 99%

Canalicular Adenoma of the Parotid Gland: A Rare Case Report and Review of Literature

Kim¹,

Paeng²,

Lee³

et al. 2017

J Clin Case Rep

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Canalicular Adenoma (CA) is an uncommon, benign salivary gland tumor that was described by the World Health Organization classification in 1991. CA has a significant predilection for occurrence in the minor salivary glands, with most cases occurring in the upper lip, followed by the buccal mucosa and palate. Rarely, CA can involve the major salivary glands, for example the parotid gland. A small number of cases of CA of the parotid gland have been reported in the literature. We report a rare case of CA on the left parotid gland of an 81-year-old man with review of literature.

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Parotid gland surgery: 4‐Year review of 118 cases in an Asian population

Abstract: This is the first report documenting that most benign parotid tumors are WT and not PA. MT risk is greater in those less than 50 with pain and a noninferior pole lesion. Cystic lesions such as WT require great care in the evaluation of FNA findings.

Cited by 25 publications

References 23 publications

Canalicular Adenoma: A Clinicopathologic and Immunohistochemical Analysis of 67 Cases with a Review of the Literature

Canalicular Adenoma: A Clinicopathologic and Immunohistochemical Analysis of 67 Cases with a Review of the Literature

Facial nerve mapping and monitoring in lymphatic malformation surgery

Canalicular Adenoma of the Parotid Gland: A Rare Case Report and Review of Literature

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