Paraneoplastic Opsoclonus-Myoclonus

Neuroblastoma presenting as opsoclonus-myoclonus: A series of six cases and review of literature

“…In adults, OMS is seen in relation to malignancies of the breast and lung (small cell carcinoma), in association with antibodies which are directed against an RNA binding antigen from the anti-Hu antibody. [ 15 ] This antibody is not found in children in OMS of NB. In children, NB which presents with OMS is more mature, shows a favorable histology, and absence of N-myc oncogene amplification than tumors which occur without symptoms of OMS.…”

Neuroblastoma presenting as opsoclonus-myoclonus: A series of six cases and review of literature

“…In adults, OMS is seen in relation to malignancies of the breast and lung (small cell carcinoma), in association with antibodies which are directed against an RNA binding antigen from the anti-Hu antibody. [ 15 ] This antibody is not found in children in OMS of NB. In children, NB which presents with OMS is more mature, shows a favorable histology, and absence of N-myc oncogene amplification than tumors which occur without symptoms of OMS.…”

“Dancing Eye Syndrome” Secondary to Opsoclonus-Myoclonus Syndrome in Small-Cell Lung Cancer

“…Paraneoplastic OMS has been associated with SCLC and breast and ovarian malignancies in adults and antineuronal antibodies have been occasionally detected [6, 7]. Among the anti-neuronal antibodies, anti-RI, a nonsurface antigen type, Zic2 antigen (anti-Zic2), and more recently adenomatous polyposis coli antigen (anti-APC) are the most frequently detected [7, 8].…”

Neuroblastoma presenting as opsoclonus-myoclonus: A series of six cases and review of literature

“…In adults, OMS is seen in relation to malignancies of the breast and lung (small cell carcinoma), in association with antibodies which are directed against an RNA binding antigen from the anti-Hu antibody. [ 15 ] This antibody is not found in children in OMS of NB. In children, NB which presents with OMS is more mature, shows a favorable histology, and absence of N-myc oncogene amplification than tumors which occur without symptoms of OMS.…”

“Dancing Eye Syndrome” Secondary to Opsoclonus-Myoclonus Syndrome in Small-Cell Lung Cancer

“…Paraneoplastic OMS has been associated with SCLC and breast and ovarian malignancies in adults and antineuronal antibodies have been occasionally detected [6, 7]. Among the anti-neuronal antibodies, anti-RI, a nonsurface antigen type, Zic2 antigen (anti-Zic2), and more recently adenomatous polyposis coli antigen (anti-APC) are the most frequently detected [7, 8].…”

Neuroblastoma presenting as opsoclonus-myoclonus: A series of six cases and review of literature

“…In adults, OMS is seen in relation to malignancies of the breast and lung (small cell carcinoma), in association with antibodies which are directed against an RNA binding antigen from the anti-Hu antibody. [ 15 ] This antibody is not found in children in OMS of NB. In children, NB which presents with OMS is more mature, shows a favorable histology, and absence of N-myc oncogene amplification than tumors which occur without symptoms of OMS.…”

“Dancing Eye Syndrome” Secondary to Opsoclonus-Myoclonus Syndrome in Small-Cell Lung Cancer

“…Paraneoplastic OMS has been associated with SCLC and breast and ovarian malignancies in adults and antineuronal antibodies have been occasionally detected [6, 7]. Among the anti-neuronal antibodies, anti-RI, a nonsurface antigen type, Zic2 antigen (anti-Zic2), and more recently adenomatous polyposis coli antigen (anti-APC) are the most frequently detected [7, 8].…”