Paralysis With Saddle-Block Anesthesia in Obstetrics

The changing pattern of spinal arachnoiditis.

“…Spinal anaesthetics were cited as the commonest aetiological factor by Winkelman et al (1953) and Austin (1972). Rosenbleum et al (1952) described six cases after 1272 spinal anaesthetics, while Kennedy et al (1945) estimated the risk of grave neurological deficit after spinal anaesthesia to be 0.5%, of which approximately half were due to spinal arachnoiditis (Kennedy et al, 1950). Particles of haemosiderin found in a biopsy specimen (Weiss et al, 1962) supported the suggestion made by Austin (1972) that faulty technique was the cause.…”

The changing pattern of spinal arachnoiditis.

“…Spinal anaesthetics were cited as the commonest aetiological factor by Winkelman et al (1953) and Austin (1972). Rosenbleum et al (1952) described six cases after 1272 spinal anaesthetics, while Kennedy et al (1945) estimated the risk of grave neurological deficit after spinal anaesthesia to be 0.5%, of which approximately half were due to spinal arachnoiditis (Kennedy et al, 1950). Particles of haemosiderin found in a biopsy specimen (Weiss et al, 1962) supported the suggestion made by Austin (1972) that faulty technique was the cause.…”

The Medical Uses of Injection into the Cerebrospinal Fluid Space (Intrathecal and Intraventricular Injection)

“…Given via either lumbar or cisternal puncture (or, in a few cases, intraventricularly using an Ommaya reservoir), methotrexate has been effective for the treatment of leukemias and meningeal carcinomatosis [15,26,42,56]. It is the most effective method for the treatment of meningeal leukemia.…”

“…Cytosine arabinoside has also been effective by the intrathecal route in the treatment of leukemias and lymphomas [46], and combination methotrexate and cytosine arabinoside has been used effectively to treat meningeal carcinomatosis [42].…”

The neuropathological effects resulting from the intrathecal injection of chemical substances

“…Thus there can be little doubt that severe neurological complications may follow spinal anaesthesia (Yaskin & Alpers, 1945;Nicholson & Eversole, 1946;Thorsen, 1947;Bergner et al, 1951;Michelsen, 1952;Rosenbaum et al, 1952;Williams, 1954;Payne & Bergentz, 1956) resulting in two types of syndrome. One is a destructive process beginning either promptly with failure of the patient to recover fully from the effects of the anaesthetic or after a varying period of several hours or even months.…”

The changing pattern of spinal arachnoiditis.

“…Spinal anaesthetics were cited as the commonest aetiological factor by Winkelman et al (1953) and Austin (1972). Rosenbleum et al (1952) described six cases after 1272 spinal anaesthetics, while Kennedy et al (1945) estimated the risk of grave neurological deficit after spinal anaesthesia to be 0.5%, of which approximately half were due to spinal arachnoiditis (Kennedy et al, 1950). Particles of haemosiderin found in a biopsy specimen (Weiss et al, 1962) supported the suggestion made by Austin (1972) that faulty technique was the cause.…”

The Medical Uses of Injection into the Cerebrospinal Fluid Space (Intrathecal and Intraventricular Injection)

“…Given via either lumbar or cisternal puncture (or, in a few cases, intraventricularly using an Ommaya reservoir), methotrexate has been effective for the treatment of leukemias and meningeal carcinomatosis [15,26,42,56]. It is the most effective method for the treatment of meningeal leukemia.…”

“…Cytosine arabinoside has also been effective by the intrathecal route in the treatment of leukemias and lymphomas [46], and combination methotrexate and cytosine arabinoside has been used effectively to treat meningeal carcinomatosis [42].…”

The neuropathological effects resulting from the intrathecal injection of chemical substances

“…Thus there can be little doubt that severe neurological complications may follow spinal anaesthesia (Yaskin & Alpers, 1945;Nicholson & Eversole, 1946;Thorsen, 1947;Bergner et al, 1951;Michelsen, 1952;Rosenbaum et al, 1952;Williams, 1954;Payne & Bergentz, 1956) resulting in two types of syndrome. One is a destructive process beginning either promptly with failure of the patient to recover fully from the effects of the anaesthetic or after a varying period of several hours or even months.…”

The changing pattern of spinal arachnoiditis.

“…Spinal anaesthetics were cited as the commonest aetiological factor by Winkelman et al (1953) and Austin (1972). Rosenbleum et al (1952) described six cases after 1272 spinal anaesthetics, while Kennedy et al (1945) estimated the risk of grave neurological deficit after spinal anaesthesia to be 0.5%, of which approximately half were due to spinal arachnoiditis (Kennedy et al, 1950). Particles of haemosiderin found in a biopsy specimen (Weiss et al, 1962) supported the suggestion made by Austin (1972) that faulty technique was the cause.…”

The Medical Uses of Injection into the Cerebrospinal Fluid Space (Intrathecal and Intraventricular Injection)

“…Given via either lumbar or cisternal puncture (or, in a few cases, intraventricularly using an Ommaya reservoir), methotrexate has been effective for the treatment of leukemias and meningeal carcinomatosis [15,26,42,56]. It is the most effective method for the treatment of meningeal leukemia.…”

“…Cytosine arabinoside has also been effective by the intrathecal route in the treatment of leukemias and lymphomas [46], and combination methotrexate and cytosine arabinoside has been used effectively to treat meningeal carcinomatosis [42].…”

The neuropathological effects resulting from the intrathecal injection of chemical substances

“…Thus there can be little doubt that severe neurological complications may follow spinal anaesthesia (Yaskin & Alpers, 1945;Nicholson & Eversole, 1946;Thorsen, 1947;Bergner et al, 1951;Michelsen, 1952;Rosenbaum et al, 1952;Williams, 1954;Payne & Bergentz, 1956) resulting in two types of syndrome. One is a destructive process beginning either promptly with failure of the patient to recover fully from the effects of the anaesthetic or after a varying period of several hours or even months.…”