Paradoxical puborectalis contraction is a feature of constipation in patients with multiple sclerosis.

Abstract

Objective-To study the disturbed anorectal physiology associated with constipation in multiple sclerosis.

Calcium polycarbophil improves constipation in non-traumatic spinal cord disorders

“…Diseases in which there is a non-traumatic spinal cord disorder are also associated with constipation, although the underlying mechanisms differ [3,4].…”

Bowel Biofeedback Treatment in Patients With Multiple Sclerosis and Bowel Symptoms

“…1,2 The neurological pathway that determines how MS affects gut function is not fully clarified, but evidence suggests that extrinsic autonomic control of bowel function can be affected, resulting in multiple alterations of gut motility and control. 4 Constipation appears to be more related to pelvic floor dyssynergia 4,7 and slow bowel transit, 4,8 and incontinence seems to depend more on anal sphincter weakness and rectal hyposensitivity. 2,4 Pelvic floor dyssynergia could be a behavioral phenomenon as in nonneurological patients, 9 or neurological in origin and parallel to bladder neck dyssynergia in MS. 6 Non-MS factors having a significant impact on symptoms might be represented by childbirth 10 and polypharmacy.…”

Autonomic dysfunction in multiple sclerosis

“…Constipation is a result of not only disease exacerbation itself, but also of decreased ambulation of patients and concomitant medications that may alter bowel movement. As well, there is evidence of paradoxical puborectalis contraction in MS, corresponding to detrusor sphincter dyssinergia in patients with bladder symptoms [56].…”