2007
DOI: 10.1590/s0365-05962007000500003
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Abstract: FUNDAMENTOS: Paracoccidioidomicose é micose sistêmica de alta prevalência no Brasil. As lesões orocutâneas são de importância para o diagnóstico e acompanhamento clínico. OBJETIVO: Quantificar e qualificar a presença de lesões cutâneas em pacientes com paracoccidioidomicose e correlacionar com forma clínica e gravidade dos casos. MÉTODOS: Realizou-se estudo clínico observacional de série de casos, classificados segundo a forma clínica, localização topográfica e morfologia da lesão quando presente. RESULTADOS: … Show more

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Cited by 50 publications
(65 citation statements)
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“…7 Frequency, number and morphology of skin lesions are consequence of the agent/host interaction. 1 Purely cutaneous disease incidence ranges between 12-15% and originates from hematogenous dissemination of the fungus; 10 of contiguous pre-existing lesion; or rarely, from direct inoculation. 1,8 The hematogenous pathway is predominant and, in general, with multiple lesions, as reported here.…”
Section: Discussionmentioning
confidence: 99%
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“…7 Frequency, number and morphology of skin lesions are consequence of the agent/host interaction. 1 Purely cutaneous disease incidence ranges between 12-15% and originates from hematogenous dissemination of the fungus; 10 of contiguous pre-existing lesion; or rarely, from direct inoculation. 1,8 The hematogenous pathway is predominant and, in general, with multiple lesions, as reported here.…”
Section: Discussionmentioning
confidence: 99%
“…1,2,3 It was originally described in Brazil, by Adolfo Lutz, in 1908. 2,3 It is endemic in the country predominantly in the south, south-east and midwest regions of Brazil.…”
Section: Introductionmentioning
confidence: 99%
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“…In addition, abusive alcohol consumption and smoking habits are constantly observed in this population [7] [8]. Pre-existing risk factors or conditions are considered and play an important role in the transformation from infection to manifest disease, since they decrease host defense mechanisms with implications for the quality of granuloma formation [9].…”
Section: Introductionmentioning
confidence: 99%
“…Paracoccidioidomycosis is a systemic infection that involves the skin in 31.2% to 54.2% of cases. 1,2 Paracoccidioidomycosis associated with malignancy is reported to occur in 0.16% to 14.1% of cases (mean 3.96%), the most commonly associated malignancy being carcinoma. 3 Compared to Histoplasma capsu-latum and even Sporothrix schenckii, Paracoccidioides brasiliensis does not fit the profile of an opportunistic fungus; however, in endemic countries, it would be no surprise to find its diagnosis associated with a clinical status of immunosuppression.…”
mentioning
confidence: 99%