Papulonecrotic tuberculid secondary to Mycobacterium bovis

Abstract

A patient with papulonecrotic tuberculid had a pruritic papular eruption associated with constitutional symptoms. The eruption flared whenever the patient received low doses of prednisone to control symptoms of temporal arteritis. A cervical lymph node biopsy specimen demonstrated acid-fast bacilli, and Mycobacterium bovis grew on the cultures. The eruption cleared completely with antituberculous therapy. This case demonstrated the clinicopathologic findings compatible with a diagnosis of papulonecrotic tuberculid. Skepticism regarding the existence of papulonecrotic tuberculid is probably a result of the current decreased prevalence of untreated tuberculosis, and the subsequently increased rarity of this entity.

Papulonecrotic tuberculid—clinicopathologic and molecular features of 12 Indian patients

“…The rate may actually be higher, depending on the fixation and age of the blocks. Other mycobacteria have also been identified, such as M. bovis and atypical mycobacteria [21]. Our findings further support a strong link between PNT and TB.…”

A case of moyamoya disease in a patient with multi-drug resistant tuberculosis

“…Also, cerebral arteritis in association with tuberculosis apart from the nervous system has been reported by some authors. 21,22 In our case, the patient had a history of hemiplegia one year back for which he did not seek any form of treatment. Also, the development of resistance to first-line anti-tubercular drugs may be associated with lack of early diagnosis and treatment in our patient.…”

Moyamoya syndrome in a known case of pulmonary tuberculosis

“…[4] On the other hand, levels of many growth factors, enzymes, and other peptides cerebral arteritis associated with tuberculous foci apart from the nervous system has been reported by some authors. [14,15] Based on these observations, though the pathologic examination for the cerebral vessels was not performed, we could hypothesize that cerebral arteritis is responsible for the angiographic changes in our patient.…”