Papillomavirus in Pregnancy Urine

Diagnostic Virology Using Electron Microscopic Techniques

“…To confirm cytologic detection of virus the urine cells with viral inclusions were embedded for thin sectioning. Recently papillomavirus particles were seen in urine from pregnant women (Lecatsas and Boes, 1979). Cytology is often more sensitive than either virus isolation or negative stain electron microscopy and reprocessing in this way has increased the diagnostic potential of the electron microscope (Coleman et al, 1980). As well as typical polyomavirus particles Lecatsas and Prozesky (1975) observed filamentous and minispherical forms in one urine.…”

Self testing for human papillomaviruses

“…HPV particles were identified in the urine of a pregnant woman as long ago as 1979. 15 The feasibility of detecting HPV DNA in the urine of women with cervical neoplasia was demonstrated in a small study that showed absolute concordance between biopsy/scrape and urine for the presence or absence of HPV-16 DNA. 16 However, comparison of HPV DNA detection by type specific PCR in cervical smears and paired urine samples showed that the sensitivity of HPV detection in urine was lower than that in cervical material.…”