volume 110, issue 2, P807-814 2021
DOI: 10.1016/j.xphs.2020.09.041
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Abstract: Finasteride is used to treat benign prostatic hyperplasia (BPH) and pattern hair loss (androgenetic alopecia or APA). The local administration of formulations with increased solubility and controlled release of finasteride are proposed using gallate-containing compositions within embolic microparticles or paste. Finasteride solubility in either epigallocatechin gallate (EGCG) or tannic acid (TA) solutions was assessed using HPLC. Poly(DL-lactide-co-glycolide) (PLGA) or poly(methylmethacrylate) (PMMA) microsphe…

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