Pancreatic Neuroendocrine Tumors: Signaling Pathways and Epigenetic Regulation
Zena Saleh,
Matthew C. Moccia,
Zachary Ladd
et al.
Abstract:Pancreatic neuroendocrine tumors (PNETs) are characterized by dysregulated signaling pathways that are crucial for tumor formation and progression. The efficacy of traditional therapies is limited, particularly in the treatment of PNETs at an advanced stage. Epigenetic alterations profoundly impact the activity of signaling pathways in cancer development, offering potential opportunities for drug development. There is currently a lack of extensive research on epigenetic regulation in PNETs. To fill this gap, w… Show more
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