1996
DOI: 10.1001/archneur.1996.00550070124020
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Pallidal Lesions

Abstract: Lesions in the GPi result in a loss of inhibitory pallidal projections to the thalamus, which may explain the hyperkinetic signs. Lesions in the GPe lead to an increased inhibition of the thalamus, which may explain the hypokinetic signs. Neuronal activation in lesion sites suggests the presence of remaining functionally vital tissue.

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Cited by 33 publications

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“…Lesions in the globus pallidus external (GPe) and internal (GPi) divisions lead to the akinetic-rigid syndrome in men [73]. …”
Section: Discussion
mentioning
confidence: 99%