Palladium-103: A new radioactive source in the treatment of unresectable carcinoma of the pancreas: A phase I–II study

Nori, Dattatreyudu; Merimsky, Ofer; Osian, Adrian; Heffernan, Margot; Cortes, Engracio P.; Turner, James

doi:10.1002/(sici)1096-9098(199604)61:4<300::aid-jso14>3.0.co;2-9

Cited by 20 publications

(8 citation statements)

References 16 publications

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“…Brachytherapy models for prostate cancer have been es− tablished elsewhere [18,19], whereas accurate models for pan− creatic cancer have not yet been developed. Recently, some in− vestigators have used 103 Pd seeds to treat pancreatic cancer [20]. The 125 I seeds cost 60 US dollars each in the present study, hence the total cost of treatment for one patient is expensive giv− en that the average number of seeds implanted in each patient is 20.…”

Section: Complications and Safety Assessmentmentioning

confidence: 72%

Endoscopic ultrasonography-guided interstitial implantation of iodine 125-seeds combined with chemotherapy in the treatment of unresectable pancreatic carcinoma: a prospective pilot study

et al. 2008

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Section: Complications and Safety Assessmentmentioning

confidence: 72%

Endoscopic ultrasonography-guided interstitial implantation of iodine 125-seeds combined with chemotherapy in the treatment of unresectable pancreatic carcinoma: a prospective pilot study

et al. 2008

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“…Chemotherapy is generally ineffective and external beam radiation is associated with significant collateral damage to the adjacent organs. EUS-guided ablation of pancreatic tumor through local delivery of radiofrequency energy, brachytherapy, immunotherapy or gene therapy is under investigation [47][48][49][50][51].…”

Section: Pancreatic Tumor Ablationmentioning

confidence: 71%

Endoscopic ultrasonography in the diagnosis and management of cancer

Pungpapong¹,

Noh²,

Wallace³

2005

Expert Review of Molecular Diagnostics

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Since its development and introduction to clinical practice, endoscopic ultrasonography (EUS) has progressed rapidly from being a purely imaging modality with limited use in the detection of small pancreatic cancers to one that can provide a tissue diagnosis by fine-needle aspiration (FNA) and deliver therapy. EUS has now firmly established a place as the investigation of choice in the diagnosis, locoregional staging and management of a wide range of gastrointestinal cancers. With the increasing use of FNA, the accuracy of EUS has substantially improved and may become a stand-alone investigation in some situations. However, it is recommended that a combination of information obtained from other imaging modalities and EUS is needed to maximize the accuracy, in particular to complete staging beyond locoregional stage. In addition to well-established indications, newer applications of EUS are emerging and are no longer limited to the gastrointestinal system. In lung cancer, EUS combined with endobronchial ultrasonography is emerging as an accurate, minimally invasive, nonsurgical alternative to staging of the mediastinum. Furthermore, the ability of EUS to acquire tissue safely and conveniently results in a potential role of the molecular diagnostics to enhance the performance of EUS-guided FNA. Besides a diagnostic role of EUS, there continues to be technological advances in the field of interventional EUS, with many potential applications under investigation. This review focuses on the current and future roles of EUS in the diagnosis and management of cancers.

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“…However, as endosonographers have become more comfortable with the linear views, it has increasingly been applied as a single instrument. The advantage of the linear scope over the radial scope is it ability to perform FNA, Doppler measurements, and therapeutics, such as fine needle injection and celiac plexus neurolysis [3,5,36,[39][40][41][42][43][44][45].…”

Section: Discussionmentioning

confidence: 99%

Changing Trends in Endosonography: Linear Imaging and Tissue are Increasingly the Issue

et al. 2007

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The indications and uses of endoscopic ultrasound (EUS) are expanding. The role of EUS-guided fine needle aspiration (EUS-FNA) is considered an essential aspect of EUS practice. A significant change in the indications and technology used for EUS has occurred. This study was designed to compare the use of radial, linear, and miniprobe endosonography equipment during a 10-year period in a single, large, EUS practice. A retrospective review of an EUS experience at a single high-volume center was performed. In this single-center experience, there has been an increase in the volume of EUS and EUS-FNA. For luminal cancer-staging cases, the radial echoendoscope is the predominant scope used for examination and has not changed significantly. In contrast, for pancreaticobiliary and mediastinal indications, the use of the linear array echoendoscope alone has increased and currently is the preferred scope for examination (33% vs. 76%, P < 0.001; 46% vs. 96%, P < 0.001). In these cases requiring EUS-FNA, the use of the linear array scope alone has increased from 17% to 73%. In this single-center experience, EUS has shifted from an imaging technology to an image-guided biopsy and therapeutic technology. The use of the linear array EUS alone has increased, especially in the evaluation of pancreatobiliary and mediastinal disease and when fine-needle aspiration is performed.

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Palladium-103: A new radioactive source in the treatment of unresectable carcinoma of the pancreas: A phase I–II study

Cited by 20 publications

References 16 publications

Endoscopic ultrasonography-guided interstitial implantation of iodine 125-seeds combined with chemotherapy in the treatment of unresectable pancreatic carcinoma: a prospective pilot study

Endoscopic ultrasonography-guided interstitial implantation of iodine 125-seeds combined with chemotherapy in the treatment of unresectable pancreatic carcinoma: a prospective pilot study

Endoscopic ultrasonography in the diagnosis and management of cancer

Changing Trends in Endosonography: Linear Imaging and Tissue are Increasingly the Issue

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