Pain on intramuscular injection of bupivacaine, ropivacaine, with and without dexamethasone

Krishnan, Suresh K.

doi:10.1053/rapm.2000.8933

Cited by 14 publications

(3 citation statements)

References 25 publications

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“…0.25% had less injection pain and better efficacy. Krishnan et al 434 RCT 30 VAS I-A Comparing injection pain of bupivacaine, ropivacaine, bupivacaine with steroids, ropivacaine with steroids, and just needle insertion. Ropivacaine was less painful (alone) compared to bupivacaine or either local anesthetic in combination with steroids.…”

Section: Injection Therapymentioning

confidence: 99%

The American Society of Pain and Neuroscience (ASPN) Evidence-Based Clinical Guideline of Interventional Treatments for Low Back Pain

Sayed¹,

Grider²,

Strand³

et al. 2022

JPR

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Introduction Painful lumbar spinal disorders represent a leading cause of disability in the US and worldwide. Interventional treatments for lumbar disorders are an effective treatment for the pain and disability from low back pain. Although many established and emerging interventional procedures are currently available, there exists a need for a defined guideline for their appropriateness, effectiveness, and safety. Objective The ASPN Back Guideline was developed to provide clinicians the most comprehensive review of interventional treatments for lower back disorders. Clinicians should utilize the ASPN Back Guideline to evaluate the quality of the literature, safety, and efficacy of interventional treatments for lower back disorders. Methods The American Society of Pain and Neuroscience (ASPN) identified an educational need for a comprehensive clinical guideline to provide evidence-based recommendations. Experts from the fields of Anesthesiology, Physiatry, Neurology, Neurosurgery, Radiology, and Pain Psychology developed the ASPN Back Guideline. The world literature in English was searched using Medline, EMBASE, Cochrane CENTRAL, BioMed Central, Web of Science, Google Scholar, PubMed, Current Contents Connect, Scopus, and meeting abstracts to identify and compile the evidence (per section) for back-related pain. Search words were selected based upon the section represented. Identified peer-reviewed literature was critiqued using United States Preventive Services Task Force (USPSTF) criteria and consensus points are presented. Results After a comprehensive review and analysis of the available evidence, the ASPN Back Guideline group was able to rate the literature and provide therapy grades to each of the most commonly available interventional treatments for low back pain. Conclusion The ASPN Back Guideline represents the first comprehensive analysis and grading of the existing and emerging interventional treatments available for low back pain. This will be a living document which will be periodically updated to the current standard of care based on the available evidence within peer-reviewed literature.

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Section: Injection Therapymentioning

confidence: 99%

The American Society of Pain and Neuroscience (ASPN) Evidence-Based Clinical Guideline of Interventional Treatments for Low Back Pain

Sayed¹,

Grider²,

Strand³

et al. 2022

JPR

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“…31 Based on a study conducted on human volunteers, it has been determined that the pain experienced during intramuscular injection of bupivacaine 0.5% is significantly more intense compared with ropivacaine 0.5%. 32 Interestingly, the variance in pain intensity between these two LAs does not appear to be associated with differences in pH. 32 Lipid solubility of the LA has also been considered as a factor in the severity of pain on injection.…”

Section: Discussionmentioning

confidence: 99%

“… 32 Interestingly, the variance in pain intensity between these two LAs does not appear to be associated with differences in pH. 32 Lipid solubility of the LA has also been considered as a factor in the severity of pain on injection. 33 This factor provides justification for the observation that bupivacaine, being more liposoluble compared with ropivacaine, may cause greater pain during injection.…”

Section: Discussionmentioning

confidence: 99%

Use of wound infusion catheters for postoperative local anaesthetic administration in cats

Kazmir-Lysak,

Torres-Cantó,

Ingraffia

et al. 2023

Journal of Feline Medicine and Surgery

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Objectives The present study aimed to document the use of the wound infusion catheter (WIC) following a variety of surgical procedures in cats, investigating complications and risk factors associated with catheter placement or local anaesthetic (LA) administration. Methods A retrospective, multicentric study was performed. Medical databases of eight veterinary referral hospitals from 2010 to 2021 were searched to identify records of cats where WICs were used. Information regarding signalment, type of surgery, size and type of WIC placed, and LA protocol used, as well as postoperative complications, were retrieved. Results One hundred and sixty-six cases fulfilled the inclusion criteria. Feline injection site sarcoma resection was the most common surgery. Overall complications were identified in 22/166 cats (13.2%). Thirteen cats (7.8%) experienced wound-related complications, whereas nine cats (5.4%) experienced drug-delivery complications. The only factor associated with an increased risk of complications was the amount of a single dose of LA delivered through the catheter ( P <0.001). An amount higher than 2.5 ml of LA delivered at each administration was associated with an increased risk of complications. All complications were minor and self-limiting. Conclusions and relevance WICs were used for a large variety of surgical procedures with different protocols of LA administration as part of a multimodal analgesic plan in cats. The risk of complications was relatively low and self-limiting, suggesting its safe use in cats. Further prospective studies are required to evaluate efficacy of postoperative analgesia and to determine the suitable protocol for WIC handling and maintenance.

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Intraoperative Management of the Laparoscopic Patient

Scott‐Conner¹

2006

The Sages Manual

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Pain on intramuscular injection of bupivacaine, ropivacaine, with and without dexamethasone

Cited by 14 publications

References 25 publications

The American Society of Pain and Neuroscience (ASPN) Evidence-Based Clinical Guideline of Interventional Treatments for Low Back Pain

The American Society of Pain and Neuroscience (ASPN) Evidence-Based Clinical Guideline of Interventional Treatments for Low Back Pain

Use of wound infusion catheters for postoperative local anaesthetic administration in cats

Intraoperative Management of the Laparoscopic Patient

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