Pain is a common problem in patients with ILD

Abstract

Background As it is less known about the prevalence and characteristics of pain in the patients with interstitial lung disease (ILD), this paper aims at determining the characteristics of the pain in the patients with ILD. Methods Subjects with ILD and health controls with the matched ages and genders completed Short Form McGill Pain Questionnaire (SF-MPQ) and part of the Brief Pain Inventory (BPI) Short Form to elicit the characteristics of the pain. The patients with ILD were also assessed through Pulmonary Function Test, Six Minutes Walking Test (6MWT), modified Medical Research Council Dyspnea Scale (mMRC) for state of the illness and measured health-related quality of life (HRQoL) by Short Form-36 (SF-36) and psychological associations by Hospital Anxiety and Depression Scale (HADS). Results A total of 63 subjects with ILD and 63 healthy controls (HC) were recruited in our study. The prevalence of the pain was 61.9% in ILD versus 25.3% in HC (P = 0.005) and the median score of the pain rank index (PRI) in ILD was higher than that in HC (P = 0.014). Chest (46.1%) accounted for the highest of overall pain locations in subjects with ILD. Associated clinical factors for pain intensity in the patients with ILD included exposure history of risk factors of ILD, with a longer distance of 6MWD (≥ 250 m), and a higher mMRC score (2–4). The patients with ILD and pain are more likely to suffer impaired HRQoL (P = 0.0014) and psychological problems (P = 0.0017, P = 0.044). Conclusion The pain is common in those with ILD and the pain intensity is associated with exposure history, 6MWD, and mMRC score. The patients with ILD and pain were possibly to suffer depression, anxiety, and impaired HRQoL.

Prevalence and quantification of thoracic pain (TP) through quantitative sensory testing (QST) in patients with chronic interstitial lung disease (cILD)

“…Our study con rms recent investigations in patients with pulmonary sarcoidosis, in whom the loss of mental well-being and concentration impairment have been reported with high frequency [29]. Similar to the observations of Shen et al [25], by using the painDETECT questionnaire we could detect more pain areas in patients with thoracic pain than in patients without thoracic pain. This was re ected by the signi cantly higher consumption of non-opioid analgesics in patients with thoracic compared to those without.…”

“…Thoracic pain seems to cause a limitation of mental well-being in patients with thoracic pain. An association between pain in patients with ILD and impaired quality of life was observed by Shen et al [25]. Our study con rms recent investigations in patients with pulmonary sarcoidosis, in whom the loss of mental well-being and concentration impairment have been reported with high frequency [29].…”

“…Similarly to the study by Shen et al [25], we did not nd a correlation between lung function tests and the intensity of thoracic pain. Nevertheless, positive correlations between total lung capacity and sensitivity to stimuli, i.e.…”

“…Thoracic pain seems to be an underestimated symptom in patients with chronic interstitial lung disease and, in general, knowledge on thoracic pain in patients with interstitial lung disease is scarce. A recent study reported that the prevalence of pain in ILD patients was 62% compared to 25% in healthy controls, with thoracic pain being the most frequent form (46%), followed by joint and limb pain [25]. In that study, the occurrence of chest pain was higher in patients with idiopathic pulmonary brosis than those with CTD-ILD.…”

A Cross-Sectional and Longitudinal Study of Pain among Middle-Aged and Older Adults in Thailand

“…Furthermore, in agreement with previous research [2,5], having certain comorbidities, such as arthritis [7] and lung diseases, increased the odds of pain. Older adults with arthritis are prone to pain disability [27], and pain is a common problem among patients with interstitial lung disease [28]. In addition, in univariable analyses, other noncommunicable diseases (NCDs), such as hypertension and diabetes were associated with pain.…”