Pagetoid dyskeratosis: Bear it in mind when observing a parallel ridge pattern on the hand

Armengot‐Carbó, Miquel; Martínez-Lahuerta, Carmen; Pitarch, Gerard

doi:10.1111/1346-8138.15026

Cited by 4 publications

(16 citation statements)

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“…In one patient, the lesion healed completely with cryotherapy 9 . Other cases improved spontaneously over months to years 4,10 . When our patient was evaluated two weeks after the biopsy, it was observed that the lesion had completely disappeared.…”

Section: Discussionmentioning

confidence: 73%

“…Recently, pigmented lesions with histopathological findings of PD in the hand region have been described. All but one of the 10 cases described in the literature were women, and more than half of the cases had palmar region involvement associated with friction due to continuous broom use 2‐4,9‐11 . Our case was a male patient with a linear lesion in the nondominant left palmar region.…”

Section: Discussionmentioning

confidence: 76%

“…9 Other cases improved spontaneously over months to years. 4,10 When our patient was evaluated two weeks after the biopsy, it was observed that the lesion had completely disappeared. In dermatology practice, spontaneous resolution following biopsy is generally is seen in reactive lesions such as keratoacanthoma and melanoacanthoma.…”

Section: Discussionmentioning

confidence: 82%

“…PRP is a very specific dermoscopic pattern for acral lentiginous melanoma, which is likely to suggest melanoma when present, and it is reported in 86% of cases. 3,4 However, it can also occur in benign conditions such as subcorneal hematoma, 12 Laugier-Hunziker-Baran syndrome, 13 and some melanocytic nevi. 14 The striking PRP presentation of all cases with dermoscopy records, including our case, suggests that PD with a hand localization should be included among these benign differential diagnoses.…”

Section: Discussionmentioning

confidence: 99%

“…1 Therefore, repetitive pressure and friction are suggested to be responsible for the etiology of this condition. 1,4 Recently, pigmented lesions with histopathological findings of PD in the hand region have been described. All but one of the 10 cases described in the literature were women, and more than half of the cases had palmar region involvement associated with friction due to continuous broom use.…”

Section: Discussionmentioning

confidence: 99%

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Pagetoid dyskeratosis with a palmar localization: Rapid resolution following biopsy

Gür

Erdoğan

Sade

2021

J of Cosmetic Dermatology

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Background: Pagetoid dyskeratosis (PD), which is found in more than 2% of skin biopsy specimens, is accepted as a histopathological finding reflecting the abnormal keratinization process. However, to date, only a limited number of cases have been described to have brown pigmentation on the hands, triggered by friction, and present with pagetoid dyskeratosis as the only sign on histopathology and a parallel ridge pattern on dermoscopy.Aim: To present and discuss the typical clinical, histopathological, and dermoscopic features of pagetoid dyskeratosis, and to draw attention to the spontaneous resolution following biopsy. Patient:We present a case of pagetoid dyskeratosis with a palmar localization, which rapidly resolved following biopsy, in a patient with no history of friction.Results: PD is the only important histopathological finding in typical irregular pigmented lesions located in the hand. PD should also be considered in the differential diagnosis of lesions that show parallel ridge pattern on the hand. Two weeks after the biopsy, disappearance of the lesion may be due to the effect of inflammatory response revealed by biopsy. Conclusions:Although the cause of this condition is not yet fully understood, most cases being associated with friction or rapid spontaneous resolution following biopsy, as in the current case, may indicate the reactive nature of the lesion. Further researches are required to be clarify etiology of PD.

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Section: Discussionmentioning

confidence: 73%

Section: Discussionmentioning

confidence: 76%