Journal of Chromatography A 2012 DOI: 10.1016/j.chroma.2012.02.037 View full text
Larry T. Taylor

Abstract: The use of additives to dramatically extend the range of solute polarity amenable to CO(2) based supercritical fluid chromatography (pcSFC) was predicted over 20 years ago. At that time additives were predicted to have multiple functions such as enhancement of mobile phase solvating power, ion suppression, and ion pairing. The adsorption of mobile phase components on the stationary phase causing a modification of its surface was predicted, but the implications for separations were not defined. Reports publishe…

expand abstract