volume 2, issue 8, PS552 2007
DOI: 10.1097/01.jto.0000283619.46414.57
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Abstract: introduced into cancer cells, in which the gene is inactivated, to restore the cell's normal gene functions. Such introduction of TSGs in the cancer cells generally induces apoptosis and/or cell cycle arrest. Gene therapy using various known and newly identified TSGs as therapeutic genes have reached clinical trials for treatment of several cancer types. However, as different types of cancers have different tumor suppressor deficiencies, the strategy must be customized to each type. Thus, the aim of this study…

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