This study was conducted to determine the alternative treatment preferences and health perceptions of those who were 18 and older in Şanlıurfa. This is a descriptive study whose population consists of individuals who are 18 and older. In the study, 482 people who volunteered to participate were reached between 01.07.2022 -01.09.2022. A socio-demographic information form and Health Perception Scale with 30 items were used to collect data, which we prepared by making a literature review. 72.2% of the individuals who participated in the study stated that they went to an herbalist/healer, one of the alternative medicine methods. Then, 57.7% of them stated that they used the prayer method and 28% of them stated that they used the cupping (hijama) method, respectively. The mean score of the health perception scale was found as higher among younger ones, university graduates, those who did not take drugs regularly, those who saw a doctor before using alternative treatment methods, and those who benefitted from the treatment which the doctor administered. Within the direction of these results, in order to increase the health perception of individuals, making attempts to raise the education level and extend GETAT (traditional and complementary medicine training) centers to enable the proper and effective use of alternative treatment may be important steps in terms of preventive health services.