"Oxytalan" Fibers of the Dermal-Epidermal Junction

Elastic fibres in the dermal papilla

“…By light microscopy, the oxytalan fibres (corresponding to the clastic fibril bundle) can be differentiated from the deeper elastic fibres by the staining methods used to characterize the elastic system fibres (Hasegawa, i960;Cotta-Pereira et ai, 1976). On the other hand, our previous report (Tsuji et ai, 1979) showed that the fibres corresponding to oxytalan fibres remained after autoclaving just as the deeper elastic fibres did, while the other components of the dermis including collagen fibres were completely removed.…”

“…Thin elastic fibres perpendicular to the dermo-epidermal junction have been noted in the papillary dermis by several investigators (Dick, 1947;Hasegawa, i960;Cooper, 1969;Cotta-Pereira, Rodrigo & Bittencourt-Sampaio, 1976)-Hasegawa (i960) stated that they are oxytalan fibres because they can be demonstrated after oxidation with peracetic add. By electron microscopy these oxytalan fibres appear as bundles of parallel fibrils (Cotta-Pereira et ai, 1976).…”

Oxytalan-Fibers—Dermal Fibromas and Giant-Cell Tendon Sheath Tumors

“…2 Although not found in the connective tissue of the normal dermis,1 they occur as a prominent component of the dermal-epidermal junction in abnormal skin. 3 The search for oxytalan fibers in pathological states so far has been directed to their identification in dental granulomas, radicular cysts,4 and sclerosing hemangiomas.5 Oxytalan fibers have now been further investigated in giant-cell tumors of tendon sheath, dermal fibromas, and keloids, all lesions the origin of which is still somewhat controversial.…”