Oxygen and Carbon Dioxide Contents of Arterial and Venous Blood of Schizophrenic Patients

Body chemistry and perception.

“…Hoskins (17) found that as a group they tend to be hypometabolic, consuming appreciably less oxygen than do nonschizophrenic individuals. According to Looney and Freeman (26), measurement of oxygen and carbon dioxide concentrations in the arterial and venous blood of schizophrenic patients indicates that sufficient amounts of oxygen get into the blood and are transported to the body tissues, but for some reason the cells fail to utilize oxygen in normal fashion. Reduction in the amount of oxygen used results in decreased production of carbon dioxide, and the latter change leads to increase in the chloride of the erythrocytes and heightened concentrations of lactic acid.…”

“…We have seen that the behavioral symptoms of schizophrenia are often referred to as disturbances of various metabolic processes and consequent abnormalities of body chemistry. It has become standard practice to conclude, as do Looney and Freeman (26), that schizophrenia is probably due to disorders of oxidative functions Ch •3] BODY CHEMISTRY AND PERCEPTION in the brain cells. Statements of this nature merely reveal the extent of our ignorance concerning the behavioral phenomena involved in the disease and' the ways in which the brain influences any sort of complex behavior.…”

Body chemistry and perception.

“…Hoskins (17) found that as a group they tend to be hypometabolic, consuming appreciably less oxygen than do nonschizophrenic individuals. According to Looney and Freeman (26), measurement of oxygen and carbon dioxide concentrations in the arterial and venous blood of schizophrenic patients indicates that sufficient amounts of oxygen get into the blood and are transported to the body tissues, but for some reason the cells fail to utilize oxygen in normal fashion. Reduction in the amount of oxygen used results in decreased production of carbon dioxide, and the latter change leads to increase in the chloride of the erythrocytes and heightened concentrations of lactic acid.…”

“…We have seen that the behavioral symptoms of schizophrenia are often referred to as disturbances of various metabolic processes and consequent abnormalities of body chemistry. It has become standard practice to conclude, as do Looney and Freeman (26), that schizophrenia is probably due to disorders of oxidative functions Ch •3] BODY CHEMISTRY AND PERCEPTION in the brain cells. Statements of this nature merely reveal the extent of our ignorance concerning the behavioral phenomena involved in the disease and' the ways in which the brain influences any sort of complex behavior.…”

Body chemistry and perception.

“…Hoskins (17) found that as a group they tend to be hypometabolic, consuming appreciably less oxygen than do nonschizophrenic individuals. According to Looney and Freeman (26), measurement of oxygen and carbon dioxide concentrations in the arterial and venous blood of schizophrenic patients indicates that sufficient amounts of oxygen get into the blood and are transported to the body tissues, but for some reason the cells fail to utilize oxygen in normal fashion. Reduction in the amount of oxygen used results in decreased production of carbon dioxide, and the latter change leads to increase in the chloride of the erythrocytes and heightened concentrations of lactic acid.…”

“…We have seen that the behavioral symptoms of schizophrenia are often referred to as disturbances of various metabolic processes and consequent abnormalities of body chemistry. It has become standard practice to conclude, as do Looney and Freeman (26), that schizophrenia is probably due to disorders of oxidative functions Ch •3] BODY CHEMISTRY AND PERCEPTION in the brain cells. Statements of this nature merely reveal the extent of our ignorance concerning the behavioral phenomena involved in the disease and' the ways in which the brain influences any sort of complex behavior.…”

Body chemistry and perception.

“…Hoskins (17) found that as a group they tend to be hypometabolic, consuming appreciably less oxygen than do nonschizophrenic individuals. According to Looney and Freeman (26), measurement of oxygen and carbon dioxide concentrations in the arterial and venous blood of schizophrenic patients indicates that sufficient amounts of oxygen get into the blood and are transported to the body tissues, but for some reason the cells fail to utilize oxygen in normal fashion. Reduction in the amount of oxygen used results in decreased production of carbon dioxide, and the latter change leads to increase in the chloride of the erythrocytes and heightened concentrations of lactic acid.…”

“…We have seen that the behavioral symptoms of schizophrenia are often referred to as disturbances of various metabolic processes and consequent abnormalities of body chemistry. It has become standard practice to conclude, as do Looney and Freeman (26), that schizophrenia is probably due to disorders of oxidative functions Ch •3] BODY CHEMISTRY AND PERCEPTION in the brain cells. Statements of this nature merely reveal the extent of our ignorance concerning the behavioral phenomena involved in the disease and' the ways in which the brain influences any sort of complex behavior.…”