Oxidativer Stress und Möglichkeiten seiner Messung aus umweltmedizinischer Sicht

Koch-Institut, Robert

doi:10.1007/s00103-008-0720-5

Cited by 8 publications

(3 citation statements)

References 131 publications

(49 reference statements)

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“…The Commission “Methods and Quality Assurance in Environmental Medicine” of the RKI has commented in detail on various diagnostic methods without sufficient scientific evidence or without a medical-scientific basis in environmental medicine [ 350 , 351 , 352 , 353 , 355 , 357 ].…”

Section: Diagnosticsmentioning

confidence: 99%

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AWMF mold guideline “Medical clinical diagnostics for indoor mold exposure” – Update 2023 AWMF Register No. 161/001

Hurraß,

Heinzow,

Walser-Reichenbach

et al. 2024

ALS

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Section: Diagnosticsmentioning

confidence: 99%

“…Table 11 shows examples of diagnostic methods without sufficient scientific evidence or without a medical or scientific basis [ 5 , 73 , 232 , 283 , 350 , 351 , 352 , 353 , 355 , 357 , 512 , 535 , 684 ]. These are not recommended due to a lack of evidence.…”

Section: Diagnosticsmentioning

confidence: 99%

AWMF mold guideline “Medical clinical diagnostics for indoor mold exposure” – Update 2023 AWMF Register No. 161/001

Hurraß,

Heinzow,

Walser-Reichenbach

et al. 2024

ALS

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“…Since mould allergens do not cause type IV sensitization, lymphocyte transformation testing for mould is not indicated as a diagnostic method [14]. …”

Section: Diagnostic Work-upmentioning

confidence: 99%

Abridged version of the AWMF guideline for the medical clinical diagnostics of indoor mould exposure

et al. 2017

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This article is an abridged version of the AWMF mould guideline “Medical clinical diagnostics of indoor mould exposure” presented in April 2016 by the German Society of Hygiene, Environmental Medicine and Preventive Medicine (Gesellschaft für Hygiene, Umweltmedizin und Präventivmedizin, GHUP), in collaboration with the above-mentioned scientific medical societies, German and Austrian societies, medical associations and experts. Indoor mould growth is a potential health risk, even if a quantitative and/or causal relationship between the occurrence of individual mould species and health problems has yet to be established. Apart from allergic bronchopulmonary aspergillosis (ABPA) and mould-caused mycoses, only sufficient evidence for an association between moisture/mould damage and the following health effects has been established: allergic respiratory disease, asthma (manifestation, progression and exacerbation), allergic rhinitis, hypersensitivity pneumonitis (extrinsic allergic alveolitis), and increased likelihood of respiratory infections/bronchitis. In this context the sensitizing potential of moulds is obviously low compared to other environmental allergens. Recent studies show a comparatively low sensitizing prevalence of 3–10% in the general population across Europe. Limited or suspected evidence for an association exist with respect to mucous membrane irritation and atopic eczema (manifestation, progression and exacerbation). Inadequate or insufficient evidence for an association exist for chronic obstructive pulmonary disease, acute idiopathic pulmonary hemorrhage in children, rheumatism/arthritis, sarcoidosis and cancer. The risk of infection posed by moulds regularly occurring indoors is low for healthy persons; most species are in risk group 1 and a few in risk group 2 (Aspergillus fumigatus, A. flavus) of the German Biological Agents Act (Biostoffverordnung). Only moulds that are potentially able to form toxins can be triggers of toxic reactions. Whether or not toxin formation occurs in individual cases is determined by environmental and growth conditions, above all the substrate. In the case of indoor moisture/mould damage, everyone can be affected by odour effects and/or mood disorders. However, this is not a health hazard. Predisposing factors for odour effects can include genetic and hormonal influences, imprinting, context and adaptation effects. Predisposing factors for mood disorders may include environmental concerns, anxiety, condition, and attribution, as well as various diseases. Risk groups to be protected particularly with regard to an infection risk are persons on immunosuppression according to the classification of the German Commission for Hospital Hygiene and Infection Prevention (Kommission für Krankenhaushygiene und Infektionsprävention, KRINKO) at the Robert Koch- Institute (RKI) and persons with cystic fibrosis (mucoviscidosis); with regard to an allergic risk, persons with cystic fibrosis (mucoviscidosis) and patients with bronchial asthma should be protected.The rational diagnos...

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Antioxidantien

Fiedler¹

2019

Springer Reference Medizin

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Oxidativer Stress und Möglichkeiten seiner Messung aus umweltmedizinischer Sicht

Cited by 8 publications

References 131 publications

AWMF mold guideline “Medical clinical diagnostics for indoor mold exposure” – Update 2023 AWMF Register No. 161/001

AWMF mold guideline “Medical clinical diagnostics for indoor mold exposure” – Update 2023 AWMF Register No. 161/001

Abridged version of the AWMF guideline for the medical clinical diagnostics of indoor mould exposure

Antioxidantien

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