Oxidative stress, melatonin level, and sleep insufficiency among electronic equipment repairers

Abstract

Background:Exposure to extremely low frequency electromagnetic field (ELF-EMF), especially among electronic equipment repairers may induce oxidative stress and affect sleep quality.Aims:This study was carried out to (a) investigate the effect of exposure to ELF-EMF on the malondialdehyde (MDA) levels among electronic equipment repairers as an indicator of oxidative stress; and melatonin hormone levels; and (b) to study the prevalence of sleep insufficiency among electronic equipment repairers exposed to ELF-EMF.Materials and Methods:A cross-sectional study was carried out on 50 electronic equipment repairers at high risk of exposure to ELF-EMF, and a matched control group at lower risk of exposure to ELF-EMF. All the participants completed a self-administered questionnaire about medical and occupational histories; and sleep sufficiency. The plasma melatonin and MDA levels of the study subjects were assessed.Results:The mean level of serum melatonin in the electronic equipment repairers was lower than that of the controls (P < 0.01). Moreover, serum MDA mean level of the electronic equipment repairers was higher than that of the controls (P < 0.01). Sleep insufficiency was more frequent among electronic equipment repairers (18.00%) in comparison with the controls (8.70%) (P > 0.05)Conclusion:The electronic equipment repairers, exposed to ELF-EMF, are at a risk of oxidative stress and sleep insufficiency, which could be explained by lower plasma melatonin levels and higher MDA levels. Health education about the hazards of ELF-EMF, shortening of exposure time per day, and taking antioxidant vitamins should be done to ameliorate the oxidative effect of EMF on those workers.

Nordihydroguaiaretic acid ameliorates cisplatin induced nephrotoxicity and potentiates its anti-tumor activity in DMBA induced breast cancer in female Sprague–Dawley rats

“…These ROS promote the formation of MDA, a lipid peroxidation end product in the kidney. The content of MDA is a good index of increased oxidative stress in the tissues, displaying raised peroxidation processes [37]. Also, they distort the normal functioning of antioxidant enzyme cascade such as SOD, catalase and GSH.…”

“…Our results showed that 5 day pre-treatment with NDGA, along with cisplatin, significantly decreased the levels of BUN and creatinine, indicating the protective effect of NDGA against cisplatin induced nephrotoxicity. MDA is a degradation product of lipid hydroperoxide, which provides an index of the peroxidation of lipids in body tissue [37]. It is well known that cisplatin causes lipid peroxidation in the kidney by generating reactive oxygen species.…”

Asupan Gizi dan Mengantuk pada Mahasiswa

“…Hal ini menunjukkan terdapat hubungan kejadian kurang tidur dengan keterpaparan gelombang elektromagnetik yang tinggi. 8 Anak dan remaja yang mempunyai durasi tidur cukup mengonsumsi media seperti menonton televisi (TV) dan menggunakan komputer yang rendah. 9 Sekitar 72% penduduk Asia cenderung menggunakan internet sebelum tidur dibanding etnik yang lain.…”

Can cytogenetics explain the possible association between exposure to extreme low‐frequency magnetic fields and Alzheimer's disease?

“…As elevated levels of oxidative stress were associated with AD, it is also important to stress that EMF effects on oxidative stress have also been reported in numerous investigations (e.g. Wolf et al ., ; Akdag et al ., ; El‐Helaly and Abu‐Hashem, ; Goraca et al ., ; Emre et al ., ). It was also found that treatment of rats with melatonin and the spin‐trap compound N‐tert ‐butyl‐ α ‐phenylnitrone could block the effect of magnetic fields on brain cell DNA, suggesting that free radicals may play a role in magnetic‐field‐induced DNA damage (Lai and Singh, ).…”