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Cited by 452 publications
(344 citation statements)
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References 58 publications
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“…In addition to classical candidate markers related to monoamines, such as platelet serotonin concentration, 2 recent studies are focusing on altered response of lymphocytes to glucose deprivation, 3 oxidative stress markers, 4 and serum/plasma brain-derived neurotrophic factor. 5 Comprehensive gene expression analysis has also been used for the identification of blood biomarkers.…”
Section: Introductionmentioning
confidence: 99%
“…In addition to classical candidate markers related to monoamines, such as platelet serotonin concentration, 2 recent studies are focusing on altered response of lymphocytes to glucose deprivation, 3 oxidative stress markers, 4 and serum/plasma brain-derived neurotrophic factor. 5 Comprehensive gene expression analysis has also been used for the identification of blood biomarkers.…”
Section: Introductionmentioning
confidence: 99%
“…[1][2][3][4] Here, we report the first en bloc assessment of this set of previously described markers of mood episodes in bipolar disorder. For that, we examined these peripheral biomarkers in different mood states of bipolar disorder and in healthy subjects.…”
mentioning
confidence: 99%
“…All assays presented in the Figure were carried out according to methodology described in previous publications from our group [3][4][5] and performed blind to subject group. The three dimensions assessed were neurotrophins (brain-derived neurotrophic factor, neurotrophin-3), oxidative stress markers (protein carbonyl content, thiobarbituric acid reactive substances, total reactive antioxidant potentials) and inflammatory markers (interleukin-6, interleukin-10 and tumor necrosis factor a).…”
mentioning
confidence: 99%
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“…Além disso, os sistemas antioxidantes também parecem estar frequentemente alterados, com aumentos significativos nos sistemas da glutationa e da superóxido dismutase 74,75,77 , provavelmente decorrentes de mecanismos compensatórios ao estado pró-oxidativo existente. Em uma metanálise recente, os níveis de óxido nítrico e dano oxidativo a lipídeos foram identificados como os marcadores sistêmicos mais consistentemente presentes em pacientes com transtorno bipolar 78 .…”
Section: Estresse Oxidativounclassified