Oxidative Stress and Testicular Torsion

Dökmeci, Dikmen

doi:10.1007/978-1-61779-776-7_17

Cited by 1 publication

(2 citation statements)

References 241 publications

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“…Moreover, spermatozoa contain an array of ROS scavengers such as SOD, catalase, and substances such as ascorbic acid, taurine, hypotaurine, albumin, and carnitine to balance any ROS high concentration. However, any increased concentration of toxic metabolic products over the ROS scavenging ability, may cause loss of sperm motility and viability[ 66 - 68 ].…”

Section: Searchmentioning

confidence: 99%

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Antioxidants in experimental ischemia-reperfusion injury of the testis: Where are we heading towards?

Vaos

Zavras

2017

WJM

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Testicular torsion (TT) is a medical emergency that primary affects newborns and young adolescents. It causes testicular injury due to the torsion of the spermatic cord and its components, initially in the venous blood flow and finally in the arterial blood flow. Prompt diagnosis and early surgical management are necessary in managing this urgent situation. The process of the pathophysiological events in ischemia-reperfusion is multifactorial and deals with the perception of the oxidative stress responsible for the consequences of ischemia/reperfusion (I/R) stress following TT. Duration and severity of torsion also play a significant role in the oxidative stress. A detrimental result of the defense system of the testes takes place resulting finally in testicular atrophy and impaired function. Antioxidant factors have been experimentally studied in an effort to front this state. They have been classified as endogenous or exogenous antioxidants. Endogenous antioxidants comprise a structure of enzymic enzymatic and non-enzymic enzymatic particles presented within cytoplasm and numerous other subunits in the cells. Exogenous antioxidants include a variety of natural and pharmaceutical agents that may prevent or ameliorate the harmful effects of I/R injury. In this study we review those factors and their ability to enhance the oxidative status of the testis. A feature insight into where we are heading is attempted.

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Section: Searchmentioning

confidence: 99%

“…In the first, the superoxide radical and hydrogen peroxide are eliminated by using specific enzymes such as SOD, catalase, and glutathione peroxidase (GPX) either by administration of these enzymes or by increasing them in vivo actions. In the second, radical production is prevented by antioxidant scavenging systems[ 66 ].…”

Section: Searchmentioning

confidence: 99%

Antioxidants in experimental ischemia-reperfusion injury of the testis: Where are we heading towards?

Vaos

Zavras

2017

WJM

View full text Add to dashboard Cite

show abstract

Oxidative Stress and Testicular Torsion

Cited by 1 publication

References 241 publications

Antioxidants in experimental ischemia-reperfusion injury of the testis: Where are we heading towards?

Antioxidants in experimental ischemia-reperfusion injury of the testis: Where are we heading towards?

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