Oxidant/Antioxidant Balance in Cows and Sheep in Antenatal Pathology

Sklyarov, Pavlo; Fedorenko, S. Y.; Naumenko, S. V.

doi:10.15421/2020_201

Cited by 3 publications

(2 citation statements)

References 15 publications

(16 reference statements)

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“…Здоров'я вимені молочних корів залежить від їх продуктивності та добробуту (Sklyarov et al, 2020). Період від запуску до отелення та рання лактація мають вирішальне значення.…”

Section: вступunclassified

Health of the dairy herd and indicators of milk quality

Zazharska

2023

SMLNUVMB

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Now a lot of attention is paid to the safety and quality of food products. Milk and dairy products are in significant demand among the population and occupy a significant segment in the variety of human food. The content of fat and protein characterize the quality of milk and are of great importance. The cost of raw materials, therefore, the farmer's profit, depends on these indicators. It is impossible to produce a high-quality product from hazardous raw materials. Cattle udder health is an important factor in animal welfare and dairy farm economics. The purpose of the research was to analyze data characterizing the health of dairy cows and milk quality indicators (fat and protein content depending on the month of the year). Collected milk from cows of the farm “Yekaterinoslavsky”, Dnipro city, was studied. Average indicators of fat and protein content per month during 2021 and 2022 are presented. Farm data were analyzed: the proportion of new cases of mastitis in dairy cows per month for 2021 and 2022. The lowest content of fat (3.47–3.65 %) and protein (3.26–3.41 %) in the cow milk is observed in the summer, which is due to the largest amount of milk obtained from cows during this period. It is accepted that the dairy herd is healthy if the proportion of cows with mastitis does not exceed 4 %. This indicator was exceeded only once – in June 2022 (4.45 %). In 2021, the highest rates of mastitis cases were observed in January and December – 2.96 and 3.05 %, respectively. The smallest share of new cases of mastitis was noted in September and November – 1.52 and 0.97 %, respectively. Perhaps this is connected with the mass launch of cows and the dry period. In 2022, the dairy herd increased by more than 100 cows, and the proportion of new cases of mastitis increased. The highest rates of mastitis cases in 2022 were observed in June and July – 4.45 and 3.84 %, respectively. The lowest proportion of new cases of mastitis was noted in August and November – 2.72 and 2.54 %, respectively. In general, the dairy herd of the dairy complex is safe from mastitis, the share of this disease is less than 4 %.

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Section: вступunclassified

Health of the dairy herd and indicators of milk quality

Zazharska

2023

SMLNUVMB

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“…Numerous stress factors that animals are exposed to in modern industrial complexes (Milostiviy et al 2017;Mota-Rojas et al 2020), lead to increased production of reactive oxygen species, causing stress and, in some cases, depletion of antioxidant defense mechanisms (Lyubin et al 2013;Zbarovskiy and Bannikov 2014). Many scientists point to a close relationship between the development of a stress response, changes in hormonal levels, and oxidativeantioxidant balance in the body (Sklyarov et al 2020). It is believed that changes in internal homeostasis under stress necessarily involve a powerful induction of free radical generation (Chauhan et al 2014;Hall et al 2014).…”

Section: Oxidative Stress and The Role Of The Antioxidant Systemmentioning

confidence: 99%

Biochemical changes during heat stress in productive animals with an emphasis on the antioxidant defense system

Mylostуva

Prudnikov

Kolisnyk

et al. 2022

JABB

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The problem of free radical pathologies in high temperatures in animal husbandry and veterinary medicine is extremely important scientific and practical. In the process of hyperthermia, the structure of cell membranes, the permeability of membranes, and membrane transport systems change, which cause the oxidation of unsaturated fatty acids and the accumulation of toxic products of a radical nature. This plays an important role in the development of many pathological conditions. The review article describes the problem of the influence of heat stress (HS) on a living organism and the problem of hyperthermia in animal husbandry. Emphasis is placed on the role of the body's antioxidant system in a state of HS and the use of antioxidant drugs as additives into feed for farm animals, aimed at mitigating the course and harmful effects in HS. On the one hand, our goal was to describe in an accessible form the main complex biochemical disorders in the body under HS conditions, which lead to a deterioration in the welfare and loss of productivity of animals. On the other hand, we tried to show the special role of the antioxidant defense system in preventing the development of oxidative stress in its classical representation. Also, we substantiated the choice in favor of using natural and synthetic antioxidants as one of the strategies for the prevention of HS in modern animal husbandry.

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Treatment of burns using polyethylene-glycol-based drugs: Dynamics of regeneration at the biochemical, cytological, histological, and organism levels of organization

Zazharskyi,

Zaslavskyi,

Sosnickyi

et al. 2024

Regul. Mech. Biosyst.

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Every year, up to 11 million burns are recorded. They are first among all traumas, leading to over 300,000 deaths around the globe every year. Burns caused by fire are also one of the main causes of deaths and disability-adjusted life years in countries with low and average levels of income. This research analyzed an experimental modeling of burn treatment using anti-burn drugs. Laboratory guinea pigs were traumatized with 2–3 degree burns with the burnt area of 15–20% of the skin surface. We compared the therapeutic efficacies of the experimental drug based on polyethylene glycol and the officinal medicinal drug – the ointment Pantestin. We assessed pathophysiological and pathomorphological changes over the process of burns, microbial landscape on the skin and in the microbiome of the internal environment of the guinea pigs. The most effective drug was the experimental anti-burn ointment based on polyethylene glycol. On the third day of the experiment, the Pantestin drug ensured the survival of 14.7% of the experimental animals compared with 57.1% survival using the ointment of the experimental drug and 100% death of the control animals that received no anti-burn therapy. The dominant bacterial pathogens that induce pathogenesis of the burn process are purulent-necrotic and toxicogenic ubiquitous prokaryotes Pseudomonas aeruginosa, hemolytic capsular variant of Escherichia coli, and Staphylococcus aureus. From the burn wound, various prokaryotic microflora were isolated, and since day three after the infliction of the burn, in microbiome of the large intestine, no more indigenous bioindicators of the macroorganism’s physiological wellbeing – Aerococcus viridans and Mycobacterium vaccae, were isolated against the background of rapid decrease in isolation of lactobacteria, bifidobacteria, and saccharolytic yeasts.

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Oxidant/Antioxidant Balance in Cows and Sheep in Antenatal Pathology

Cited by 3 publications

References 15 publications

Health of the dairy herd and indicators of milk quality

Health of the dairy herd and indicators of milk quality

Biochemical changes during heat stress in productive animals with an emphasis on the antioxidant defense system

Treatment of burns using polyethylene-glycol-based drugs: Dynamics of regeneration at the biochemical, cytological, histological, and organism levels of organization

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