Management of Prader-Willi Syndrome 1988
DOI: 10.1007/978-1-4684-0316-9_1 View full text |Buy / Rent full text
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“…People with PWS exhibited sleep characteristics which differed from those of the non‐disabled control group. In support of previous findings, they were highly likely to exhibit EDS (Alexander & Hanson 1988; Cassidy et al . 1990; Helbing‐Zwanenburg et al .…”
Section: Discussionsupporting
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“…People with PWS exhibited sleep characteristics which differed from those of the non‐disabled control group. In support of previous findings, they were highly likely to exhibit EDS (Alexander & Hanson 1988; Cassidy et al . 1990; Helbing‐Zwanenburg et al .…”
Section: Discussionsupporting
“…Sleep disturbances are also reported to be one of the characteristics of subjects with PWS (Alexander & Hanson 1988) and Holm et al . (1993) listed sleep disturbances as a minor criterion for the disorder.…”
Section: Introductionmentioning
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“…The Prader-Willi Syndrome (PWS) is a rare disease first described by Prader et al (1956), and is not related to sex (Burd et al 1990) or other factors such as race, social class, or geographical origin (Alexander and Hanson 1988;Butler and Thompson 2000). Genetic research has shown that PWS is rarely inherited and the recurrence risk within the same family is normally low (Buiting and Horsthemke 2006).…”
Section: Clinical Characteristics Of the Prader-willi Syndrome And Thmentioning
“…Genetic research has shown that PWS is rarely inherited and the recurrence risk within the same family is normally low (Buiting and Horsthemke 2006). It must be emphasized that although PWS has a relative low incidence (it affects one in every 10,000-15,000 humans) (Lewis et al 2002;Dimitropoulos et al 2013), it is one of the most frequent syndromes among those recognized (Alexander and Hanson 1988). In a simplistic way, the reason why this malformation occurs is related to the fact that, at conception, the crossing over that happens between the 23 paternal and the 23 maternal chromosomes, when they line up to form 46 chromosomes, is imperfect, which causes health and cognitive "abnormalities" in the individual.…”
Section: Clinical Characteristics Of the Prader-willi Syndrome And Thmentioning