volume 66, issue 7, P4154-4160 1992
DOI: 10.1128/jvi.66.7.4154-4160.1992
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T Huang, J Pavlovic, P Staeheli, M Krystal

Abstract: The murine Mx1 protein is an interferon-inducible protein which confers selective resistance to influenza virus infection both in vitro and in vivo. The precise mechanism by which the murine Mx1 specifically inhibits replication of influenza virus is not known. Previously, sensitive replication systems for influenza virus ribonucleoprotein, in which a synthetic influenza virus-like ribonucleoprotein is replicated and transcribed by influenza virus proteins provided in trans, have been developed. With these sys…

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