Outcomes of pregnancies complicated by hyperemesis gravidarum

Kuru, Oğuzhan; Sen, Serhat; Akbayır, Özgür; Goksedef, Behiye Pinar Cilesiz; Özsürmeli, Mehmet; Attar, Erkut; Saygili, Halil

doi:10.1007/s00404-011-2176-3

Cited by 33 publications

(43 citation statements)

References 21 publications

(27 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A link between hyperemesis gravidarum and placental dysfunction disorders was first suggested in a 1991 case-control study reporting a 1.6 times higher risk for preeclampsia in women with severe vomiting [43]. Consistent with our findings, previous studies also showed no increased risks of placenta dysfunction disorders with exposure to hyperemesis [44, 45]. The largest cohort to date with 1,155,033 pregnancies, of which 13,287 were complicated by hyperemesis leading to hospital admission, showed a slightly increased risk for preeclampsia, and a higher risk for pre-term preeclampsia when hyperemesis occurred in the second trimester [15].…”

Section: Discussionsupporting

confidence: 91%

Hyperemesis gravidarum and placental dysfunction disorders

Koudijs

Savitri

Browne

et al. 2016

BMC Pregnancy Childbirth

View full text Add to dashboard Cite

BackgroundEvidence about the consequence of hyperemesis gravidarum (HG) on pregnancy outcomes is still inconclusive. In this study, we evaluated if occurrence of hyperemesis gravidarum is associated with placental dysfunction disorders and neonatal outcomes.MethodsA prospective cohort study was conducted in a maternal and child health primary care referral center, Budi Kemuliaan Hospital and its branch, in Jakarta, Indonesia. 2252 pregnant women visiting the hospital for regular antenatal care visits from July 2012 until October 2014 were included at their first clinic visit. For women without, with mild and with severe hyperemesis, placental dysfunction disorders (gestational hypertension, preeclampsia (PE), stillbirth, miscarriage), neonatal outcomes (birth weight, small for gestational age (SGA), low birth weight (LBW), Apgar score at 5 min, gestational age at delivery) and placental outcomes (placental weight and placental-weight-to-birth-weight ratio (PW/BW ratio)) were studied.ResultsCompared to newborns of women without hyperemesis, newborns of women with severe hyperemesis had a 172 g lower birth weight in adjusted analysis (95%CI -333.26; -10.18; p = 0.04). There were no statistically significant effects on placental dysfunction disorders or other neonatal outcome measures.ConclusionsThe results of our study suggest that hyperemesis gravidarum does not seem to induce placental dysfunction disorders, but does, if severe lead to lower birth weight.

show abstract

Section: Discussionsupporting

confidence: 91%

Hyperemesis gravidarum and placental dysfunction disorders

Koudijs

Savitri

Browne

et al. 2016

BMC Pregnancy Childbirth

View full text Add to dashboard Cite

show abstract

“…Similar results were reported by Roseboom et al (2011) (comparing 237 HG to 2,190 non-HG women) and by Dodds et al (2006), Bailit et al (2005) and Zhang and Cai (1991). Conversely, data from other authors such as Oguzhan Kuru et al (2012), Bashiri et al (1995) and Hallak et al (1996) suggest that HG is not significantly correlated with adverse pregnancy outcomes and SGA babies. The differences in outcomes reported could be attributed to the differences in population and to how ' smallness ' is defined.…”

Section: Discussionmentioning

confidence: 72%

Pregnancy outcomes in severe hyperemesis gravidarum in a multi-ethnic population

Vlachodimitropoulou-Koumoutsea

Gosh

Manmatharajah

et al. 2013

Journal of Obstetrics and Gynaecology

View full text Add to dashboard Cite

We evaluated pregnancy outcomes among women with hyperemesis gravidarum (HG) in a North London multi-ethnic population. A retrospective case-control study was performed on records of obstetric admissions during a 4-year period, at North Middlesex University Hospital in North London. A total of 208 women with HG were identified according to Fairweather's criteria occurring in the first 20 weeks of pregnancy, which is severe enough to require admission to hospital. The control study group consisted of 208 women without HG, matched for age, ethnicity and parity. Maternal characteristics as well as pregnancy outcomes were compared in the two groups. The incidence of a delivery of a small-for-gestational-age (SGA) neonate below the 10th per centile was significantly higher in the HG group compared with unaffected pregnancies (8.7% vs 16.8%, p = 0.01). Hyperemesis gravidarum in a multi-ethnic population in North London is associated with SGA neonates.

show abstract

“…93 Few studies have shown an increased incidence of low birth-weight and prematurity in the babies of these patients. 94,95 The aim of treatment is to ameliorate symptoms, correct dyselectrolytemia and prevent any complications.…”

Section: Hyperemesis Gravidarum (Hg)mentioning

confidence: 99%

Pregnancy-Related Liver Disorders

Goel

Jamwal

Ramachandran

et al. 2014

Journal of Clinical and Experimental Hepatology

View full text Add to dashboard Cite

Pregnancy-related liver disorders accounted for 8% of all maternal deaths at our center from 1999 to 2011. Of the three pregnancy-related liver disorders (acute fatty liver of pregnancy (AFLP), HELLP (Hemolysis, elevated liver enzymes, low platelets) syndrome and pre-eclamptic liver dysfunction, which can lead to adverse maternal and fetal outcome, AFLP is most typically under -diagnosed. Risk of maternal death can be minimised by timely recognition and early/aggressive multi-specialty management of these conditions. Urgent termination of pregnancy remains the cornerstone of therapy for some of these life threatening disorders, but recent advancements in our understanding help us in better overall management of these patients. This review focuses on various aspects of pregnancy-related liver disorders. ( J CLIN EXP HEPATOL 2014;4:151-162) A ny liver disorder can occur co-incidentally in pregnancy. Pregnancy can also occur in a patient with pre-existent chronic liver disorder/portal hypertension. In addition, liver dysfunction in pregnancy can also be secondary to pregnancy (i.e. pregnancy-related liver disorders). The 5 pregnancy-related liver disorders-acute fatty liver of pregnancy (AFLP), HELLP syndrome (hemolysis, elevated liver enzymes and low platelets), pre-eclamptic liver dysfunction, intrahepatic cholestasis of pregnancy (ICP) and hyperemesis gravidarum-occur in different gestational time periods.

show abstract

Outcomes of pregnancies complicated by hyperemesis gravidarum

Abstract: Hyperemesis gravidarum is not associated with adverse pregnancy outcomes.

Cited by 33 publications

References 21 publications

Hyperemesis gravidarum and placental dysfunction disorders

Hyperemesis gravidarum and placental dysfunction disorders

Pregnancy outcomes in severe hyperemesis gravidarum in a multi-ethnic population

Pregnancy-Related Liver Disorders

Contact Info

Product

Resources

About